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Pathogenic Mechanism of C9orf72 haploinsufficiency in ALS/FTLD: a road to therapeutic discovery
https://braincanada.ca/fr/subventions-financées/pathogenic-mechanism-of-c9orf72-haploinsufficiency-in-als-ftld-a-road-to-therapeutic-discoveryIn this Hudson project, the team led by Dr. Robertson will pursue a comprehensive understanding of the normal functions of C9ORF72 and provide a better determination of whether loss of these functions via mutation may cause or contribute to ALS. Project Overview In this Hudson project, the team led...
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Pathogenic mechanisms of C9ORF72 repeat expansion in ALS and development of therapeutics
https://braincanada.ca/fr/subventions-financées/pathogenic-mechanisms-of-c9orf72-repeat-expansion-in-als-and-development-of-therapeuticsDr. Patten started his research career as a PhD student at the University of Alberta under the supervision of Dr. Declan Ali in 2004. Project Overview Dr. Patten started his research career as a PhD student at the University of Alberta under the supervision of Dr. Declan Ali in 2004. There he...
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Patient-reported outcome measures for social robots in dementia care
https://braincanada.ca/fr/subventions-financées/patient-reported-outcome-measures-for-social-robots-in-dementia-careImproving independence and quality of life for persons living with dementia (PLWD) and their care partners can be realized by complementing human care with robotic assistive technologies. Project Overview Improving independence and quality of life for persons living with dementia (PLWD) and their...
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Penser différemment : l'autisme dans les communautés des Premières nations
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/penser-différemment-l-autisme-dans-les-communautés-des-premières-nationsBruno Grant, lauréat du prix d'excellence Shireen et Edna Marcus de Brain Canada, s'efforce de mieux comprendre l'autisme dans les communautés des Premières nations de Maskwacis. Située dans le centre de l'Alberta, la communauté crie des plaines de Maskwacis définit les troubles du spectre...
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Percer les mystères de la maladie d'Alzheimer : Prix de la recherche sur la maladie d'Alzheimer de la Colombie-Britannique
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/percer-les-mystères-de-la-maladie-d-alzheimer-prix-de-la-recherche-sur-la-maladie-d-alzheimer-du-bcPercer les mystères de l'Alzheimer : BC Alzheimer's Research Award, un partenariat de 7,5 millions de dollars entre Brain Canada, la Michael Smith Foundation for Health Research (MSFHR), Genome BC et la Pacific Alzheimer Research Foundation (PARF). Vidéo non disponible.
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Personalized medicine for Bipolar disorder: clinical lithium response as a guide to mode of action and biomarker discovery using human neurons and biofluids
https://braincanada.ca/fr/subventions-financées/personalized-medicine-for-bipolar-disorder-clinical-lithium-response-as-a-guide-to-mode-of-action-and-biomarker-discovery-using-human-neurons-and-biofluidsBipolar Disorder (BD) is a chronic psychiatric illness, ranking in the top 10 causes of disability and mortality worldwide, due to suicide and cardiovascular death. Project Overview Bipolar Disorder (BD) is a chronic psychiatric illness, ranking in the top 10 causes of disability and mortality...
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PET imaging of Alzheimer’s-induced inflammation to monitor progression and therapy response using a novel fructose-based radiotracer
https://braincanada.ca/fr/subventions-financées/pet-imaging-of-alzheimer-s-induced-inflammation-to-monitor-progression-and-therapy-response-using-a-novel-fructose-based-radiotracerOne of the key processes driving Alzheimer’s Disease is inflammation in the brain, the severity of which may predict the severity of disease. Project Overview One of the key processes driving Alzheimer’s Disease is inflammation in the brain, the severity of which may predict the severity of...
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Phenotyping of Alzheimer’s disease across imaging-defined stages of cerebral amyloid angiopathy
https://braincanada.ca/fr/subventions-financées/phenotyping-of-alzheimer-s-disease-across-imaging-defined-stages-of-cerebral-amyloid-angiopathyMixed dementia is the most common form of dementia. Project Overview Background: Mixed dementia is the most common form of dementia. It occurs when Alzheimer’s disease (AD) combines with vascular disease, affecting both the blood vessels and the immune function in our brain. As this happens, memory...
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Physical fingerprints of single extracellular vesicles for liquid biopsy in brain cancer
https://braincanada.ca/fr/subventions-financées/physical-fingerprints-of-single-extracellular-vesicles-for-liquid-biopsy-in-brain-cancerNeed for project: Glioblastoma (GBM) is an incurable brain cancer that changes rapidly confounding standard diagnostic and therapeutic methods. Project Overview Need for project: Glioblastoma (GBM) is an incurable brain cancer that changes rapidly confounding standard diagnostic and therapeutic...
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Pictures of Resilience: A PAR Photovoice Mental Health Needs Assessment with Migrant Kalaalleq Youth Living in Copenhagen
https://braincanada.ca/fr/subventions-financées/pictures-of-resilience-a-par-photovoice-mental-health-needs-assessment-with-migrant-kalaalleq-youth-living-in-copenhagenThis project will be a participatory action research project launched in collaboration with the Greenlandic House of Copenhagen Project Overview This project will be a participatory action research project launched in collaboration with the Greenlandic House of Copenhagen, a heritage and cultural...
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