Multi-Investigator Research Initiative

The purpose of the Multi-Investigator Research Initiative (MIRI) grants is to support multidisciplinary teams and to accelerate novel and transformative research that will fundamentally change our understanding of nervous system function and dysfunction and their impact on health. The ultimate goal is to reduce the social and economic burden of neurological and mental health problems by prevention, early diagnosis, and treatment.

Proposals can address any aspect of nervous system function or dysfunction that has relevance to neurological and/or psychiatric diseases and conditions, including those of the special senses and the peripheral nervous system. The focus of proposals must be on investigating commonalities among multiple or related neurological and/or psychiatric conditions. The proposal must show how the research will generate findings applicable to multiple nervous system diseases or conditions.



The Brain Canada - Alzheimer’s Prevention Initiative Program

Brain Canada, the Banner Alzheimer’s Foundation, Novartis and industry, wish to support excellent translational research in the area of Alzheimer’s disease prevention through the efforts of Canadian teams of scientists. The ultimate goal of the initiative is to encourage Canadian researchers to perform one or more ”value-added” MIRI research project(s) that takes advantage of the APOE4 trial resources and population to answer significant research question(s) related to Alzheimer disease and associated disorders.

This program is currently being reviewed and the process is halted until this review is complete. We apologize for any inconvenience this may cause.


RBC-Brain Canada Research Partnership in Mental Health Services for Children and Youth
Multi-Investigator Research Initiative (MIRI)
Request for Applications

The RBC – Brain Canada Research Partnership will support a multi-investigator three-year research project focused on improved delivery of mental health services through the identification and validation of innovative interventions and practices that are cost-effective, and delivered at the right place and time to support both affected individuals and their families. Notably, the funded project will involve a continuing collaboration between researchers, policy-makers, service providers, and those affected by child and youth mental health issues. The collaboration will jointly identify the research questions to be studied, be engaged in the research project itself, and cooperate in the dissemination of the projects' findings to influence policy and practice.

Deadline for Receipt of Letters of Intent: 16.00 EST, Apr 3, 2015

Click here to view the Request for Application and here to submit a Letter of Intent (LOI)

The 2015 Multi-Investigator Research Initiative (MIRI) Sponsored Opportunity

Brain Canada’s MIRI grants support multidisciplinary teams for three years and usually provide up to $500,000 a year for a total of $1.5 M. The research focus may be related to any area of neural function and dysfunction, including special senses, neurological and mental health, and may involve biomedical, clinical, health services or population health approaches.

Request for Applications (RFA) announcement: December 18, 2014
Deadline for Letter of Intent: 16.00 EST, February 9, 2015

Click here to view the Request for Application and here to submit a Letter of Intent (LOI)

Funding Partners:
Beyond Batten Disease Foundation


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The 2013 Multi-Investigator Research Initiative (MIRI) Sponsored Opportunity launched on November 6, 2013.

Click here to view the "List of Funded Projects"

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The 2012 Multi Investigator Research Initiative (MIRI) was launched on May 17, 2012.

Click here to view the "List of Funded Projects" and here to view the "List of Full Application Review Committee Members"


For further Information:

About Brain Canada and the Canada Brain Research Fund:

About the MIRI competition and application process, please contact