Directory of funded grants

Filter by

534 results found

Modulating memory circuits: focal DBS treatments to improve medial temporal lobe function

  • Program Type

    Team grants

  • Area of research

    Multiple

  • Disease Area

    Alzheimer’sEpilepsy

  • Competition

    2014 MIRI Team Grants

  • Province

    Ontario

  • Start Date

    2015

  • Total Grant Amount

    $1,387,295

  • Health Canada Contribution

    $693,647

Project Overview

Two diseases that show very different trajectories have nevertheless led researchers to identify dysfunction in a common brain network. The diseases in question are Alzheimer’s disease, a devastating neurodegenerative disorder, and temporal lobe epilepsy, the most common type of partial-seizure epilepsy, characterized by brief episodes of abnormally synchronous neural activity.…

Biomarkers for Crossing the Translational Divide in Acute Spinal Cord Injury

  • Program Type

    Team grants

  • Area of research

    Injury

  • Disease Area

    Brain Injury

  • Competition

    2014 MIRI Team Grants

  • Province

    British Columbia

  • Start Date

    2015

  • Total Grant Amount

    $2,775,000

  • Health Canada Contribution

    $1,387,500

Project Overview

Each year, over 1,500 Canadians sustain an acute spinal cord injury (SCI), and join close to 40,000 across our nation living with one of the most physically and psychologically devastating of injuries. Unfortunately, none of the promising treatments that have emerged from animal models of SCI have demonstrated convincing neurologic…

Adolescent Mental Health

  • Program Type

    Team grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    2014 MIRI Team Grants

  • Province

    Alberta

  • Start Date

    2015

  • Total Grant Amount

    $1,387,285

  • Health Canada Contribution

    $693,643

Project Overview

Most mental disorders begin in adolescence; however, there are many gaps in our understanding of youth mental health. Clinical and policy gaps arise from our current inability to predict, from amongst all youth who experience mild behavioural disturbances, who will go on to develop an illness, what that illness will…

Targeting the Synaptic Pathway in Neurodevelopmental and Psychiatric Disorders

  • Program Type

    Team grants

  • Area of research

    Multiple

  • Disease Area

    AutismMental illness

  • Competition

    2014 MIRI Team Grants

  • Province

    British Columbia

  • Start Date

    2015

  • Total Grant Amount

    $1,387,500

  • Health Canada Contribution

    $693,750

Project Overview

Autism spectrum disorders are neurodevelopmental disorders characterized by deficits in social interaction, poor communication, and restricted, stereotyped patterns of behavior. Autism and schizophrenia affect over 1% of the population, and each has strong genetic associations with 60-90% heritability among twins. Recent research identified mutations in a shared genetic pathway in…

The Frontier Trial – Field Randomization of NA-1 Treatment In Early Responders

  • Program Type

    Team grants

  • Area of research

    Injury

  • Disease Area

    Stroke

  • Competition

    2014 MIRI Team Grants

  • Province

    British Columbia

  • Start Date

    2016

  • Total Grant Amount

    $8,068,664

  • Health Canada Contribution

    $3,956,135

Project Overview

Stroke is a life threatening emergency caused by blocked arteries that affects 45,000 Canadians a year. Each hour a stroke is left untreated means brain cells are dying. The only emergency treatment we have is a clot busting agent that can re-open blocked arteries if given within 3-4.5 hours of…