Directory of funded grants

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534 results found

Understanding stress to improve mental health

  • Program Type

    Team grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    2014 MIRI Team Grants

  • Province

    Alberta

  • Start Date

    2015

  • Total Grant Amount

    $1,387,500

  • Health Canada Contribution

    $693,750

Project Overview

Recent estimates indicate that 1 in 5 Canadians are affected annually by mood, anxiety and other mental illnesses. These issues are exacerbated by stress. This is important because an acute episode of stress is the most common trigger for breakthrough presentations of many mental illnesses, and when stress-related disorders are…

Prevention of Alzheimer’s Dementia in High Risk Populations: A Randomized Controlled Trial of a Combination of Cognitive Remediation and Brain Stimulation

  • Program Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Chagnon Family and Brain Canada Interventions for Prevention of Alzheimer Disease and Related Disorders (ADRD) MIRI

  • Province

    Ontario

  • Start Date

    2014

  • Total Grant Amount

    $11,196,085

  • Health Canada Contribution

    $4,998,044

Project Overview

This project is studying a novel intervention in 250 older persons whose major depression has been successfully treated with an antidepressant medication: a combination of cognitive remediation (CR, consisting of memory and problem solving exercises) plus transcranial Direct Current Stimulation (tDCS, a non-painful low electrical current that circulates through the…

Structural and functional networks in Autism Spectrum Disorder and Fragile X Syndrome

  • Program Type

    Team grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Azrieli Neurodevelopment Research Program

  • Province

    Québec

  • Start Date

    2014

  • Total Grant Amount

    $2,492,735

  • Health Canada Contribution

    $1,246,368

Project Overview

Many childhood disorders, such as Autism Spectrum Disorder (ASD) or Fragile X Syndrome (FXS), are a result of abnormal growth and connections throughout the brain, rather than being caused by some specific pathology, such as a tumour. For meaningful diagnosis, prognosis and intervention for these devastating disorders to be able…

Réseaux structurels et fonctionnels dans les troubles du spectre de l’autisme et le syndrome de l’X fragile

  • Program Type

    Team grants

  • Area of research

    Neurodéveloppemental

  • Competition

    Azrieli Neurodevelopment Research Program

  • Province

    Québec

  • Start Date

    2014

  • Total Grant Amount

    $2,492,735

  • Health Canada Contribution

    $1,246,368

Project Overview

Many childhood disorders, such as Autism Spectrum Disorder (ASD) or Fragile X Syndrome (FXS), are a result of abnormal growth and connections throughout the brain, rather than being caused by some specific pathology, such as a tumour. For meaningful diagnosis, prognosis and intervention for these devastating disorders to be able…

Treatment strategies for Autism Spectrum Disorders and Fragile-X Syndrome using mouse models, via translational control modulators

  • Program Type

    Team grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Azrieli Neurodevelopment Research Program

  • Province

    Québec

  • Start Date

    2014

  • Total Grant Amount

    $1,235,000

  • Health Canada Contribution

    $617,500

Project Overview

Aberrant control of protein synthesis (also termed translation) leads to pathological conditions like cancer, obesity, memory impairment and has been hypothesized to cause the development of Autism Spectrum Disorders (ASD) and Fragile-X syndrome (FXS). Synaptic connections are regulated by translation, thus impaired translational control is postulated to cause ASD. It…