Directory of funded grants

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534 results found

Human MiniPromoters for Restricted Expression of Ocular Gene Therapy

  • Program Type

    Platform grants

  • Area of research

    Sensory system

  • Disease Area

    Other

  • Competition

    CQDM - Brain Canada - Focus on Brain

  • Province

    British Columbia

  • Start Date

    2015

  • Total Grant Amount

    $1,496,062

  • Health Canada Contribution

    $637,136

Project Overview

The purpose of this project is to develop promoters. Promoters are pieces of DNA, which act as switches to turn genes on and off. Such promoters are important tools for drug companies working on developing gene-based therapies; known as gene therapies. These are a type of biological therapy, somewhat like…

Using synthetic antibody parts to construct antibody-based imaging devices – anti-EGFR molecular targeted imaging probes for diagnosing and monitoring glioblastoma

  • Program Type

    Team grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Canadian Cancer Society Innovation Grants

  • Province

    Saskatchewan

  • Start Date

    2017

  • Total Grant Amount

    $195,968

  • Health Canada Contribution

    $97,984

Project Overview

To improve outcomes in brain cancer, better tools are needed to diagnose brain cancer, surgically remove brain tumours and monitor how they respond to therapy. Glioblastomas, aggressive brain cancers, are treated by surgical removal of the tumour followed by radiation and chemotherapy. A molecule found on the surface of cells…

Molecular characterization of transcriptional repressor capicua in GBM

  • Program Type

    Team grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Canadian Cancer Society Innovation Grants

  • Province

    Ontario

  • Start Date

    2017

  • Total Grant Amount

    $196,000

  • Health Canada Contribution

    $98,000

Project Overview

Malignant gliomas, including oligodendrogliomas (OD) and glioblastomas (GBM), are currently incurable brain tumours with few effective treatment options. A better understanding of the molecular underpinnings of glioma is required to find new and better treatments. The goal of this study is to investigate the function of a protein that turns…

Integrative discovery of ion channels as drug targets in glioblastoma

  • Program Type

    Team grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Canadian Cancer Society Innovation Grants

  • Province

    Ontario

  • Start Date

    2017

  • Total Grant Amount

    $196,000

  • Health Canada Contribution

    $98,000

Project Overview

Ion channel (IC) proteins are known to be involved in different human diseases such as heart and brain disorders. There are many drugs that activate or inactivate ICs and they are used to treat patients with these diseases. However, less has been known about the role of ICs in cancer…

The feasibility of hyperpolarized 13C-Pyruvate MRI for monitoring patients with intracranial metastasis

  • Program Type

    Team grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Canadian Cancer Society Innovation Grants

  • Province

    Ontario

  • Start Date

    2017

  • Total Grant Amount

    $187,915

  • Health Canada Contribution

    $939,575

Project Overview

Surgery and radiation are standard treatments for cancer that has spread to the brain. Recent research has revealed that cancer cells with high levels of the chemical lactate are aggressive and resist radiation therapy. Dr Charles Cunningham will study whether an enhanced imaging method that can detect lactate can help…