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The Canadian Neurophotonics Platform
Project Overview
Dr. De Koninck studies the persistent changes in spinal cord function that occur after nervous system injury that lead to chronic pain. Understanding the long term alterations that occur in the spinal cord after injury will allow Dr. De Koninck and his team to find new treatment and prevention avenues for…
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See the project and researchersThe Experimental Imaging Centre: a Local Brain Canada Platform for Preclinical MR Neuroimaging
Project Overview
The Experimental Imaging Centre Brain Canada Platform provides state of the art pre-clinical imaging to the neuroscience research community. The core technology is a 9.4T MRI with associated animal care and physiological monitoring aimed at rat and mouse models of human neuropathology. MRI has evolved over the past decades as…
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See the project and researchersThe Ontario Brain Epigenomics Platform
Project Overview
One of the frontiers in neuroscience is to understand the molecular dynamics of the brain functions. In addition to genetic and environmental modulation, the brain is also controlled by epigenetic mechanisms. These are chemical modifications of our genetic template that regulate gene activity in response to internal or external cues.…
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See the project and researchersHuman inducible pluripotent stem cells (iPSC) platform
Project Overview
Studies of genetic disorders are limited because of the lack of appropriate tissue samples from patients. A promising avenue to overcome this deficit is the recently described method of converting adult cells into inducible pluripotent stem cells (iPSC)1, and differentiating them into desired cell types such as various types of…
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See the project and researchersManitoba Neuroimaging Platform
Project Overview
Complex research questions in neurology are often most effectively addressed by monitoring brain structure and function in human patients and live animals in experimental disease models. Recent advances in radiology, computational analysis and medical physics have made it possible to accomplish this like never before. Despite this, research is hindered…