737 results found
Prenatal serotonin reuptake inhibitor (SRI) antidepressant exposure on brain development, cognition and activity related risk for obesity: A longitudinal study with 10 year olds
Project Overview
Dr. Hutchison‘s training is in lifespan psychology and her research broadly focuses on children’s cognitive and social development. her current research project examines cognitive and health outcomes in children whose mothers’ were treated with antidepressant medication during pregnancy. About 10- 20% of women experience depressed mood during pregnancy and Serotonin…
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See the project and researchersImmunotherapy as a targeted low-impact treatment of paediatric brain cancers
Project Overview
The existing treatment regimens for children with ependymomas are generally not successful and if successful survivors are left with considerable disabilities including severely diminished IQ, focal neurological and language deficits, and endocrine deficiencies. Dr. Donovan's current proposal aims to develop an improved targeted therapy, which will increase survival rates, and…
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See the project and researchersInvestigating Blood Brain Barrier Permeability in an Experimental Model of Juvenile Stroke Using Advanced MR Imaging
Project Overview
Stroke is one of the leading causes of cerebral palsy in children that carried to term, and 60% have lifelong consequences. Currently, treatment of childhood stroke is limited to prevention of more strokes. Dr. Domi’s research uses specialized imaging techniques to study the role of the blood-brain barrier, a mechanism…
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See the project and researchersThe Effects of Glucocorticoids on the Developing Brain
Project Overview
The hippocampus has the highest concentration of glucocorticoid receptors in the brain, and is therefore a primary target for glucocorticoids. The fetus may be exposed to increased levels of glucocorticoids as a result of maternal stress/anxiety, or by maternal treatment with synthetic glucocorticoids (sGC); ~10% of all pregnant women are…
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See the project and researchersMaternal care and child neurodevelopment: A longitudinal gene x environment analysis of socio-emotional development with an integrated approach
Project Overview
Maternal depression, particularly during pregnancy, has been well established as a risk factor for child socio-emotional problems. However, the impact varies across the population, as some individuals are resilient. Their genetic architecture may hold the secrets to the differential susceptibility. Mr. Chen’s research looks at how genomic risk profile for…