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552 results found

A Novel Zebrafish-Based Platform for Anticonvulsant Drug Development

  • Program Type

    Platform grants

  • Area of research

    Injury

  • Disease Area

    Epilepsy

  • Competition

    2014 Platform Grants

  • Province

    Alberta

  • Start Date

    2015

  • Total Grant Amount

    $2,731,867

  • Health Canada Contribution

    $1,365,934

Project Overview

Epilepsy is a common neurological condition that affects 1-2% of the population. Despite dozens of anticonvulsant medications, over a third of patients remain refractory to drugs and our goal is to uncover novel therapies for this patient population. Here, we propose to create a national platform for anticonvulsant drug discovery.…

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A National biobank and database for patients with traumatic brain injury

  • Program Type

    Platform grants

  • Area of research

    Injury

  • Disease Area

    Brain Injury

  • Competition

    2014 Platform Grants

  • Province

    Ontario

  • Start Date

    2015

  • Total Grant Amount

    $2,775,000

  • Health Canada Contribution

    $1,387,500

Project Overview

Traumatic brain injury is the leading cause of death and disability in children and young adults in Canada. Despite huge developments in basic neuroscience, no new therapies or diagnostic tests have been introduced in clinical care over the past 30 years. In the acute setting, neither clinicians nor researchers are…

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Le Consortium d’Imagerie en Neurosciences et santé mentale de Québec: leader régional en neuroimagerie humaine

  • Program Type

    Platform grants

  • Area of research

    Multiple

  • Competition

    2014 Platform Grants

  • Province

    Québec

  • Start Date

    2015

  • Total Grant Amount

    $138,750

  • Health Canada Contribution

    $69,375

Project Overview

Le Consortium d’Imagerie en Neurosciences et santé mentale de Québec (CINQ) est un regroupement de chercheurs pluridisciplinaires ayant pour but le développement de la neuroimagerie dans la région de Québec. Depuis sa création en 2009, le CINQ a connu un taux de croissance fulgurant, passant de quatre à 138 chercheurs…

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Early Postnatal Metabolic Treatment for the Fetal Alcohol Syndrome

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Other

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Ontario

  • Start Date

    2016

  • Total Grant Amount

    $110,000

  • Health Canada Contribution

    $55,000

Project Overview

Fetal Alcohol Syndrome (FAS) is the result of in utero alcohol exposure and is characterized by central nervous system developmental impairments which causes lifelong physical and cognitive disabilities. The mechanisms of the impaired brain development are poorly understood, but they seem to be related with the decreased levels of antioxidants…

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Co-clinical trials of autism in mice and humans

  • Program Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Ontario

  • Start Date

    2016

  • Total Grant Amount

    $70,000

  • Health Canada Contribution

    $35,000

Project Overview

Autism is a neuro-developmental disorder characterized by social/communication deficits and repetitive behaviours. It is very heterogeneous, with over 250 genes implicated, but is highly heritable. The current therapeutic approach is frequently ineffective partly because often a single treatment is given to a heterogeneous patient population. This project will address the…

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