737 results found
A Human System to study Immune-Ependymal Cell Relationships
Project Overview
Ependymal cells are a largely understudied barrier cell type in the brain that provide a wall between brain tissue and brain fluid (cerebral spinal fluid, CSF), playing an important role in regulating fluid balance. These cells become dysfunctional in many brain diseases and this dysfunction contributes to neurodegeneration that occurs…
Project Complete
See the project and researchersDetection of tandem repeat expansion in neurological disorders
Project Overview
In the past decade, rapid development of software has allowed detection of a wide variety of genetic risk factors in brain disorders. It has improved clinical diagnosis and gene discovery for numerous human brain disorders. However, the casual genetic risk factors identified so far generally confer less risk than expected…
Project Complete
See the project and researchersNeural predictors of theta burst stimulation
Project Overview
In Canada, 1 in 20 people live with depression. Substantial efforts have been made over the years to develop new treatments to enhance therapeutic options. One effective alternative to medication is theta burst stimulation (TBS). This technique uses magnetic fields applied to the outside of the head to modulate brain…
Project Ongoing
See the project and researchersMulti-scale analyses of brain connectivity and dynamics in autism spectrum conditions
Project Overview
Autism spectrum disorder (ASD) affects approximately 1 in 70 children and is associated to a considerable burden for affected individuals, their families, and health care at large. As ASD remains not very well understood from a neuroscientific perspective, we currently lack diagnostic and intervention approaches that target potential biological mechanisms.…
Project Ongoing
See the project and researchers2019 Dr. Hubert van Tol Travel Fellowship
Project Overview
I was selected to present a poster during one of the 2 poster sessions. The project I presented was aimed at deciphering the molecular function of the Boc receptor in axon guidance. This receptor is necessary for the activation of Shh signaling but how Boc receptor binding to Shh triggers…