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Restoration of mitochondrial function by activation of the NAD+/Sirtuin pathway to treat PD
https://braincanada.ca/fr/subventions-financées/restoration-of-mitochondrial-function-by-activation-of-the-nad-sirtuin-pathway-to-treat-pdParkinson’s Disease (PD) is a debilitating neurodegenerative disease for which there is no cure. Project Overview Parkinson’s Disease (PD) is a debilitating neurodegenerative disease for which there is no cure. The cardinal motor symptoms of PD are caused by the massive loss of neurons in a region...
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Restoration of visual function: a cellular reprogramming and bioengineering approach
https://braincanada.ca/fr/subventions-financées/restoration-of-visual-function-a-cellular-reprogramming-and-bioengineering-approachThe retina is the part of the eye that is responsible for processing visual information. Project Overview The retina is the part of the eye that is responsible for processing visual information. Loss of neurons (nerve cells) in the central nervous system, which includes the brain and retina, is a...
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Restoring Cerebrovascular Health in Alzheimer’s Disease by Targeting Molecular Damage in the Neurovascular Unit
https://braincanada.ca/fr/subventions-financées/restoring-cerebrovascular-health-in-alzheimer-s-disease-by-targeting-molecular-damage-in-the-neurovascular-unitAlzheimer’s disease is linked to the build-up of harmful proteins in the brain and damage to brain blood vessels. In many people, especially in later life, this build-up happens because the brain cannot clear these proteins effectively. Our research focuses on understanding how aging damages the...
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Restoring Hippocampal Disinhibition to Reverse Early Memory Deficits in Alzheimer’s Disease
https://braincanada.ca/fr/subventions-financées/restoring-hippocampal-disinhibition-to-reverse-early-memory-deficits-in-alzheimer-s-diseaseAlzheimer’s disease can affect memory and thinking by changing how brain cells communicate. Our project looks at early changes in the hippocampus, a part of the brain important for learning and memory. Project Overview Alzheimer’s disease can affect memory and thinking by changing how brain cells...
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Retrouver ses mots
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/retrouver-ses-motsAu Canada, un AVC survient toutes les sept minutes, et les personnes qui y survivent et qui sont atteintes d’aphasie la décrivent souvent comme l’une des pertes les plus dévastatrices qui soient. Les idées sont toujours là. La personne est toujours bien présente. Mais les mots lui échappent ou...
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RGNEF modulates protein misfolding in ALS
https://braincanada.ca/fr/subventions-financées/rgnef-modulates-protein-misfolding-in-alsDiscoveries made in Canada by the lab of Dr. Michael Strong over the past few years have implicated a protein called Rho guanidine nucleotide exchange factor (RGNEF) both pathologically and genetically in causing ALS. Project Overview Discoveries made in Canada by the lab of Dr. Michael Strong over...
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Rising Star Award in Mental Health Research, in memory of Vivian Distler
https://braincanada.ca/fr/subventions-financées/rising-star-award-in-mental-health-research-in-memory-of-vivian-distlerPersonalized Modeling and Optimization of Transcranial Temporal Interference Stimulation in Major Depressive Disorder Project Overview Personalized Modeling and Optimization of Transcranial Temporal Interference Stimulation in Major Depressive Disorder Depression affects nearly 2 million...
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Rising Star Award in Mental Health Research, in memory of Vivian Distler
https://braincanada.ca/fr/subventions-financées/rising-star-award-in-mental-health-research-in-memory-of-vivian-distler-1The Role of the Hypocretin-Dorsal Raphe Nucleus Circuit in Chronic Social Isolation and Acute Social Stress Project Overview The Role of the Hypocretin-Dorsal Raphe Nucleus Circuit in Chronic Social Isolation and Acute Social Stress Social behaviour is especially sensitive to stress, and isolation...
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Road to Mental Readiness for Families and other Supportive Relationships
https://braincanada.ca/fr/subventions-financées/road-to-mental-readiness-for-families-and-other-supportive-relationshipsFirst responders, whose jobs commit them to persistent, repeated exposure to potentially triggering incidents, are at ongoing risk of developing mental health problems Project Overview First responders, whose jobs commit them to persistent, repeated exposure to potentially triggering incidents, are...
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Roche Canada investit plus de 2 millions de dollars dans l'étude de cohorte prospective canadienne visant à comprendre l'évolution de la sclérose en plaques (CanProCo)
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/roche-canada-investit-2-millions-dans-une-étude-de-cohorte-prospective-canadienne-visant-à-comprendre-la-progression-de-la-sclérose-en-plaques-canprocoToronto, ON - 3 avril 2019 - La Société canadienne de la sclérose en plaques, la Fondation Cerveau Canada et Biogen Canada ont le plaisir d'annoncer l'ajout de Hoffmann-La Roche Limited (Roche Canada) et sa contribution de 2,125 millions de dollars à l'Étude de cohorte prospective canadienne pour...