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Targeting the immune suppressive microenvironment in histone 3-mutant high-grade gliomas
https://braincanada.ca/fr/subventions-financées/targeting-the-immune-suppressive-microenvironment-in-histone-3-mutant-high-grade-gliomasThe immune system is responsible for protecting the body against diseases, but it can also play a role in tumor formation. Project Overview The immune system is responsible for protecting the body against diseases, but it can also play a role in tumor formation. By exploring the role of these cells...
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Targeting the microbiota-gut-brain axis with diet and exercise interventions in individuals with subjective cognitivedecline
https://braincanada.ca/fr/subventions-financées/targeting-the-microbiota-gut-brain-axis-with-diet-and-exercise-interventions-in-individuals-with-subjective-cognitivedeclineIndividuals with or at increased risk of Alzheimer’s disease (AD) have an altered community of microbes(microbiome) within the intestinal tract. Project Overview Individuals with or at increased risk of Alzheimer’s disease (AD) have an altered community of microbes(microbiome) within the intestinal...
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Targeting the Synaptic Pathway in Neurodevelopmental and Psychiatric Disorders
https://braincanada.ca/fr/subventions-financées/targeting-the-synaptic-pathway-in-neurodevelopmental-and-psychiatric-disordersAutism spectrum disorders are neurodevelopmental disorders characterized by deficits in social interaction, poor communication, and restricted, stereotyped patterns of behavior. Project Overview Autism spectrum disorders are neurodevelopmental disorders characterized by deficits in social...
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Targeting the telomere maintenance pathway for cancer diagnostics and therapeutics.
https://braincanada.ca/fr/subventions-financées/targeting-the-telomere-maintenance-pathway-for-cancer-diagnostics-and-therapeuticsCancer can exhibit relentless growth and relapse because of the enhanced protection of its chromosome ends. Project Overview Cancer can exhibit relentless growth and relapse because of the enhanced protection of its chromosome ends. Dr. Uri Tabori is a world expert in telomeres – the protective...
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Targeting the USP19 deubiquitinating enzyme for the treatment of Alzheimer’s disease
https://braincanada.ca/fr/subventions-financées/targeting-the-usp19-deubiquitinating-enzyme-for-the-treatment-of-alzheimer-s-diseaseAlzheimer’s disease progresses over time due to the spreading of aggregates of tau protein and amyloid protein from unaffected to affected regions of the brain. Project Overview Alzheimer’s disease progresses over time due to the spreading of aggregates of tau protein and amyloid protein from...
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Teaching Adolescents with type 1 Diabetes Self-compassion (TADS) to reduce diabetes distress: A randomized controlled trial
https://braincanada.ca/fr/subventions-financées/teaching-adolescents-with-type-1-diabetes-self-compassion-tads-to-reduce-diabetes-distress-a-randomized-controlled-trialSelf-compassion is a practice that involves acting the same way towards yourself as you would with friends and loved ones, and that you are kind and understanding towards yourself. Project Overview Self-compassion is a practice that involves acting the same way towards yourself as you would with...
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TECC-T1D3: Technology-enabled Comprehensive Care for young adults with Type 1 Diabetes and Diabetes Distress
https://braincanada.ca/fr/subventions-financées/tecc-t1d3-technology-enabled-comprehensive-care-for-young-adults-with-type-1-diabetes-and-diabetes-distressDiabetes distress, the negative emotional feelings resulting from living with diabetes and the burden of selfmanagement, is a very common challenge for people living with type 1 diabetes affecting approximately 40%. Project Overview Diabetes distress, the negative emotional feelings resulting from...
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Temps d’écran et développement du cerveau: Recherche, avantages, risques et politiques
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/le-temps-passé-devant-un-écran-et-le-développement-du-cerveau-recherche-avantages-risques-et-politiqueLa table ronde Temps d’écran et développement du cerveau : Recherche, avantages, risques et politiques, organisée par Brain Canada et accueillie par le Centre canadien de politique scientifique, s’est concentrée sur l’impact de la technologie numérique, ou temps d’écran, sur les enfants et les...
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Tester les avantages de l'écriture expressive chez les jeunes
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/tester-les-avantages-de-l-écriture-expressive-chez-les-jeunesL'adolescence peut être une période très stressante. Les adolescents doivent souvent faire face à toute une série de problèmes, allant des brimades aux conflits avec les amis, en passant par les problèmes avec les membres de la famille. Il a été démontré qu'aider les adolescents à développer leur...
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Testing therapeutic approaches to improve cognitive dysfunction in a primate model of Alzheimer’s Disease
https://braincanada.ca/fr/subventions-financées/testing-therapeutic-approaches-to-improve-cognitive-dysfunction-in-a-primate-model-of-alzheimer-s-diseaseAlzheimer’s Disease (AD) is a severe dementia that is likely a result of years of buildup in the brain of molecules called amyloid-beta oligomers (AβOs). Project Overview Alzheimer’s Disease (AD) is a severe dementia that is likely a result of years of buildup in the brain of molecules called...