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Un traitement efficace de la dépression post-partum améliore-t-il le développement cérébral et le comportement chez l’enfant ?
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/un-traitement-efficace-de-la-dépression-post-partumDes chercheuses canadiennes font l’essai d’une application conçue pour traiter la dépression post-partum et l’anxiété, et déterminent si une meilleure santé mentale chez la mère influe sur le développement cérébral de l’enfant. Un essai clinique financé par la Fondation Brain Canada et Bell Cause...
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Un traitement efficace pour les cas difficiles de cancer du cerveau chez l’enfant
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/faire-fonctionner-le-traitement-du-cancer-du-cerveau-chez-l-enfantFutur leader, Vijay Ramaswamy et son équipe de recherche ont trouvé une stratégie pour réduire le nombre de traitements que les enfants doivent subir, en particulier ceux qui sont atteints de médulloblastome récurrent et à haut risque. Le Dr Vijay Ramaswamy (à droite) est neuro-oncologue et...
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Un événement satellite inoubliable des Futurs leaders
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/evenement-satellite-futurs-leaders-montrealDes chercheurs en début de carrière, des mentors et des partenaires se sont réunis à Montréal pour définir les prochaines étapes de la recherche sur le cerveau. SUR LA PHOTO : Jiannis Taxidis, futur leader canadien de la recherche sur le cerveau, présentant une mise à jour sur son projet « Le rôle...
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Uncover regulators of key glioblastoma cell states and test their therapeutic potential
https://braincanada.ca/fr/subventions-financées/uncover-regulators-of-key-glioblastoma-cell-states-and-test-their-therapeutic-potentialTumors continuously change towards more aggressive and resistant forms. Project Overview Tumors continuously change towards more aggressive and resistant forms. Brain tumors illustrate the quandary of cancer evolution: despite standard-of-care treatment, the disease invariably progress and returns....
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Uncovering the nanoscale underpinnings of cognitive decline
https://braincanada.ca/fr/subventions-financées/uncovering-the-nanoscale-underpinnings-of-cognitive-declineEven in the healthy brain, ageing is commonly associated with cognitive decline. Project Overview Even in the healthy brain, ageing is commonly associated with cognitive decline. The factors that could explain large inter-individual differences in the progression of the decline are still poorly...
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Uncovering the pathological processes underlying neuronal dysfunction and loss in models of Parkinson’s disease
https://braincanada.ca/fr/subventions-financées/uncovering-the-pathological-processes-underlying-neuronal-dysfunction-and-loss-in-models-of-parkinson-s-diseaseThe aims of the proposal were to examine the mechanism of how dopamine neurons degenerate in Parkinson (PD) animal models. Project Overview The aims of the proposal were to examine the mechanism of how dopamine neurons degenerate in Parkinson (PD) animal models. The work was centered on three...
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Understand mTOR hyperactivation during cellular interactions using a single-cell approach
https://braincanada.ca/fr/subventions-financées/understand-mtor-hyperactivation-during-cellular-interactions-using-a-single-cell-approachThe human brain is vulnerable to too much of mTOR signaling, An important neuronal pathway regulating neuronal development and activity. Project Overview The human brain is vulnerable to too much of mTOR signaling, An important neuronal pathway regulating neuronal development and activity. We study...
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Understanding addiction through zebrafish: unveiling new solutions
https://braincanada.ca/fr/subventions-financées/understanding-addiction-through-zebrafish-unveiling-new-solutionsAddiction is a massive issue that spans generations and cultures. Project Overview Addiction is a massive issue that spans generations and cultures. Understanding and learning to help those suffering from addiction should continue to be a high- priority topic. Whether it’s looking to the past for...
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Understanding brain development and maintenance via spatial transcriptomics
https://braincanada.ca/fr/subventions-financées/understanding-brain-development-and-maintenance-via-spatial-transcriptomicsWe identified changes in the gene called IRF2BPL (Interferon Regulatory Factor 2 Binding Protein Like) as the cause of a severe brain disorder in children called NEDAMSS (Neurodevelopmental disorder with abnormal movements, loss of speech and seizures). Project Overview We identified changes in the...
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Understanding cerebral blood flow control in humans after cannabis use
https://braincanada.ca/fr/subventions-financées/understanding-cerebral-blood-flow-control-in-humans-after-cannabis-useCannabis is one of the most commonly used recreational substances in Canada, yet its effects on brain blood flow remain poorly understood. Project Overview Cannabis is one of the most commonly used recreational substances in Canada, yet its effects on brain blood flow remain poorly understood....