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Using Alzheimer’s blood biomarkers to evaluate the effect of photobiomodulation in patients with Mild Cognitive Impairment
https://braincanada.ca/fr/subventions-financées/using-alzheimer-s-blood-biomarkers-to-evaluate-the-effect-of-photobiomodulation-in-patients-with-mild-cognitive-impairmentEvery day, over 350 Canadians are diagnosed with dementia, and this number is expected to grow rapidly. Project Overview Every day, over 350 Canadians are diagnosed with dementia, and this number is expected to grow rapidly. Mild Cognitive Impairment (MCI) is an early stage where memory problems...
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Using mobile technology to inform driving decision-making in dementia
https://braincanada.ca/fr/subventions-financées/using-mobile-technology-to-inform-driving-decision-making-in-dementiaA major challenge in dementia care is determining the point at which driving becomes significantly compromised for people with dementia (PWD). Project Overview A major challenge in dementia care is determining the point at which driving becomes significantly compromised for people with dementia...
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Using neuroimaging to predict recovery from acute brain injury
https://braincanada.ca/fr/subventions-financées/using-neuroimaging-to-predict-recovery-from-acute-brain-injuryWhen a person suffers a severe brain injury, whether from an accident, stroke, or infection, clinicians struggle to predict if they will recover. Project Overview When a person suffers a severe brain injury, whether from an accident, stroke, or infection, clinicians struggle to predict if they will...
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Using Novel Approaches for Early Recognition of TIA, Heart Failure, and Connections with Vascular Dementia (UNEARTH CVD)
https://braincanada.ca/fr/subventions-financées/using-novel-approaches-for-early-recognition-of-tia-heart-failure-and-connections-with-vascular-dementia-unearth-cvdIn this program, we will study: 1) patients with stroke, which occurs when blood flow is stopped to a part of the brain causing weakness or loss of sensation;2) patients with heart failure which is when the heart does not pump properly or does not relax; 3) patients with dementia, which is deficit...
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Using synthetic antibody parts to construct antibody-based imaging devices – anti-EGFR molecular targeted imaging probes for diagnosing and monitoring glioblastoma
https://braincanada.ca/fr/subventions-financées/using-synthetic-antibody-parts-to-construct-antibody-based-imaging-devices-anti-egfr-molecular-targeted-imaging-probes-for-diagnosing-and-monitoring-glioblastomaTo improve outcomes in brain cancer, better tools are needed to diagnose brain cancer, surgically remove brain tumours and monitor how they respond to therapy. Project Overview To improve outcomes in brain cancer, better tools are needed to diagnose brain cancer, surgically remove brain tumours and...
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Using targeted ultrasound to get immunotherapy drugs past the blood-brain barrier
https://braincanada.ca/fr/subventions-financées/using-targeted-ultrasound-to-get-immunotherapy-drugs-past-the-blood-brain-barrierStephanie Borlase is investigating ways to improve immunotherapies to treat people whose lung cancer has spread to the brain, improving outcomes. Project Overview Stephanie Borlase is investigating ways to improve immunotherapies to treat people whose lung cancer has spread to the brain, improving...
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Utiliser des poissons tropicaux pour trouver des traitements contre les troubles cérébraux
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/l-utilisation-de-poissons-tropicaux-pour-trouver-des-traitements-contre-les-troubles-cérébrauxLa stratégie traditionnelle de développement de médicaments basés sur des cibles (criblage in vitro) n'a pas eu beaucoup de succès dans le développement de nouveaux médicaments. La grande majorité des nouveaux médicaments expérimentaux (IND) échouent dans les essais cliniques en raison de leur...
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Utilizing next generation intersectional approaches to define the roles of POMC neuron subpopulations
https://braincanada.ca/fr/subventions-financées/utilizing-next-generation-intersectional-approaches-to-define-the-roles-of-pomc-neuron-subpopulationsThe central nervous system controls numerous processes, including appetite and body weight regulation. Project Overview The central nervous system controls numerous processes, including appetite and body weight regulation. Given the alarming rise in global obesity, understanding how the CNS...
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Validation of cognitive rehabilitation program adapted to the needs of adults with brain cancer and adult survivors of childhood brain cancer.
https://braincanada.ca/fr/subventions-financées/validation-of-cognitive-rehabilitation-program-adapted-to-the-needs-of-adults-with-brain-cancer-and-adult-survivors-of-childhood-brain-cancerWe propose a randomized controlled trial to evaluate the efficacy of Goal Management Training (GMT) for improving these patients’ cognitive functioning as well as patient and caregiver QoL. Project Overview We propose a randomized controlled trial to evaluate the efficacy of Goal Management...
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Validation of Connexins and Pannexins as a target for Alzheimer’s Disease
https://braincanada.ca/fr/subventions-financées/validation-of-connexins-and-pannexins-as-a-target-for-alzheimer-s-diseaseAlzheimer’s Disease (AD) is the most common cause of dementia, accounting for over two thirds of cases. As of 2013, there are over 44 million people with dementia worldwide. Project Overview Alzheimer’s Disease (AD) is the most common cause of dementia, accounting for over two thirds of cases. As...