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500,000 Canadians have dementia, a number that will double within a generation due to the ongoing aging demographics of the population, with annual costs estimated to increase from $15B currently to over $150B by the year 2050. Project Overview 500,000 Canadians have dementia, a number that will...

TDP-43 is a protein that behaves abnormally in the motor neurons of 97 per cent of people with ALS. Project Overview TDP-43 is a protein that behaves abnormally in the motor neurons of 97 per cent of people with ALS. It is usually found in the nucleus, but in people with ALS, it becomes trapped...

La plateforme financée par la Fondation Brain Canada permet de nouvelles technologies pour la découverte de médicaments, afin de traiter un large éventail de maladies et de troubles cérébraux, allant de l’épilepsie et l’autisme en passant par les tumeurs cérébrales et la SLA La Dre Kurrasch et sa...

“Vascular pathology, such as loss of neurovascular coupling and disruption of the blood-brain barrier (BBB), has been documented in Huntington’s disease (HD). Project Overview “Vascular pathology, such as loss of neurovascular coupling and disruption of the blood-brain barrier (BBB), has been...

The goal of this study is to advance knowledge regarding the association of vascular risk factors and blood vessels with brain structure and function in youth with severe mental illness. Project Overview The goal of this study is to advance knowledge regarding the association of vascular risk...

Because of low fitness and heart problems, people with stroke are at very high risk of a second stroke or heart attack within 10 years. Project Overview Because of low fitness and heart problems, people with stroke are at very high risk of a second stroke or heart attack within 10 years. Exercise...

Points forts du forum public "Towards a Cure" sur la recherche sur la maladie d'Alzheimer et la démence, organisé par la Michael Smith Foundation for Health Research.

Groupe de cellules exprimant la huntingtine mutante (en rouge) in vitro. Les ponctuations jaunes sont des agrégats de huntingtine mutante et de p62, une protéine impliquée dans l'élimination des agrégats de protéines. La maladie de Huntington (MH) est une maladie héréditaire qui entraîne un...

Brain Canada et Brain Changes Initiative ont récemment annoncé un financement de 1,1 million de dollars pour de nouvelles recherches sur le cerveau au Canada dans le cadre du programme Subventions à l'innovation pour l'impact de la recherche sur les lésions cérébrales traumatiques. Deux des trois...