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2024 Dr. Hubert van Tol Travel Fellowship Jordan Lee, a Postdoctoral Fellow at the University of Calgary, investigates the impact of spinal cord injury on the autonomic nervous system and how this leads to subsequent cardiovascular dysfunction. Project Overview Jordan Lee, a Postdoctoral Fellow at...

2024 Dr. Hubert van Tol Travel Fellowship Vincent Bazinet, a Doctoral student at McGill University, aims to develop standardized workflows for high-resolution 7T MRI to provide clearer and more detailed insights into brain structure and function. Project Overview Vincent Bazinet, a Doctoral...

Medical imaging has changed how we study and treat brain degeneration. Project Overview Medical imaging has changed how we study and treat brain degeneration. The best tool for imaging subtle changes to brain proteins is positron emission tomography (or PET). But that has limited availability. An...

Challenge: Delivery of therapeutic proteins to the brain has been a longstanding barrier to CNS drug development. Project Overview Challenge: Delivery of therapeutic proteins to the brain has been a longstanding barrier to CNS drug development. Protein replacement or supplementation strategies hold...

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with no known cure, leading to progressive loss of motor function and ultimately death. Project Overview Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with no known cure, leading to progressive loss of motor...

Individuals with an incurable condition marked by decline and intolerable suffering and where death is reasonably foreseeable, as with dementia, now have access to medical assistance in dying (MAID). Project Overview Individuals with an incurable condition marked by decline and intolerable...

The LINGO-1 protein is strongly associated with Alzheimer’s disease and is a novel drug target. Project Overview The LINGO-1 protein is strongly associated with Alzheimer’s disease and is a novel drug target. LINGO-1 is a transmembrane protein that negatively regulates neuronal survival and...

Neurological and psychiatric diseases and disorders affect more than half the population. Project Overview Neurological and psychiatric diseases and disorders affect more than half the population. These disorders of the nervous system can span a range of illnesses, including generalized anxiety...

Ependymal cells are a largely understudied barrier cell type in the brain that provide a wall between brain tissue and brain fluid (cerebral spinal fluid, CSF), playing an important role in regulating fluid balance. Project Overview Ependymal cells are a largely understudied barrier cell type in...

Ischemic stroke, caused by a blood clot in the brain, is a leading cause of death, disability, and dementia. Project Overview Ischemic stroke, caused by a blood clot in the brain, is a leading cause of death, disability, and dementia. One in four of these strokes happens in patients who already had...