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Plateforme ouverte canadienne des neurosciences (CONP)
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/plate-forme-canadienne-ouverte-de-neurosciences-conp -
Platform for Neurology Biomarker Innovation
https://braincanada.ca/fr/subventions-financées/platform-for-neurology-biomarker-innovationInnovative methods that enable brain-derived proteins to be measured in blood samples are transforming the field of neurology. For example, it is now possible to use a blood test to help diagnose Alzheimer’s Disease and to monitor treatment in Multiple Sclerosis. This project will establish The...
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Polygenic applications of aging to brain and cognitive reserve in multiple sclerosis
https://braincanada.ca/fr/subventions-financées/polygenic-applications-of-aging-to-brain-and-cognitive-reserve-in-multiple-sclerosisReserve is someone’s ability to tolerate age-related changes and disease-related insults to their brain without developing symptoms. Project Overview Reserve is someone’s ability to tolerate age-related changes and disease-related insults to their brain without developing symptoms. How reserve...
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Portable Low Field MRI for Application in Multiple Sclerosis
https://braincanada.ca/fr/subventions-financées/portable-low-field-mri-for-application-in-multiple-sclerosisMultiple Sclerosis (MS) is a disease that attacks the nerves in the brain, making it difficult for the brain to send signals to the rest of the body. MS symptoms are extremely variable, and can include difficulty walking, fatigue, pain, and cognitive issues such as problems with concentration,...
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Post-mortem human hippocampal neuroplasticity, cognition, and late-life physical activity: Importance of biological sex and cognitive health status
https://braincanada.ca/fr/subventions-financées/post-mortem-human-hippocampal-neuroplasticity-cognition-and-late-life-physical-activity-importance-of-biological-sex-and-cognitive-health-statusThe world population is rapidly aging; there is a real need for effective, personalized lifestyle recommendations for promoting healthy cognitive aging. Project Overview The world population is rapidly aging; there is a real need for effective, personalized lifestyle recommendations for promoting...
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Pourquoi les neurosciences ouvertes ?
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/pourquoi-les-neurosciences-ouvertesPour les millions de Canadiens touchés par les troubles cérébraux, les réponses ne viennent pas assez vite. C'est pourquoi Brain Canada estime qu'il est impératif de réunir les chercheurs pour qu'ils partagent leurs connaissances. "Ce que nous voulons, c'est la bonne réponse, pas la première",...
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Pre-clinical drug discovery against hexanucleotide repeat-containing C9orf72 toxicity using Caenorhabditis elegans and patient-derived induced motor neurons
https://braincanada.ca/fr/subventions-financées/pre-clinical-drug-discovery-against-hexanucleotide-repeat-containing-c9orf72-toxicity-using-caenorhabditis-elegans-and-patient-derived-induced-motor-neuronsA few years ago, Dr. Parker and researchers in his lab genetically engineered worms that mimicked human ALS through motor neuron degeneration and paralysis. Project Overview A few years ago, Dr. Parker and researchers in his lab genetically engineered worms that mimicked human ALS through motor...
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Precision diagnosis and prognosis of primary and metastatic brain tumours using DNA methylation profiling in liquid biopsy
https://braincanada.ca/fr/subventions-financées/precision-diagnosis-and-prognosis-of-primary-and-metastatic-brain-tumours-using-dna-methylation-profiling-in-liquid-biopsyNeed for project: More sensitive molecular tools are needed in the field of neuro-oncology to enable early detection, more accurate diagnosis, and prediction of outcome for brain tumors. Project Overview Need for project: More sensitive molecular tools are needed in the field of neuro-oncology to...
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Precision in Space and Time: Brain State-Dependent Stimulation Using Real-Time EEG and TMS
https://braincanada.ca/fr/subventions-financées/precision-in-space-and-time-brain-state-dependent-stimulation-using-real-time-eeg-and-tmsThe goal of this project is to develop new principles to treat brain disease and investigate brain function using non-invasive neurostimulation, without the side-effects of drugs. Project Overview The goal of this project is to develop new principles to treat brain disease and investigate brain...
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Precision Metabolism: Deciphering and Targeting Metabolic Adaptations in Therapy-Resistant Recurrent Glioblastoma
https://braincanada.ca/fr/subventions-financées/precision-metabolism-deciphering-and-targeting-metabolic-adaptations-in-therapy-resistant-recurrent-glioblastomaGlioblastoma (GBM) is a common and deadly brain cancer in adults. Project Overview Glioblastoma (GBM) is a common and deadly brain cancer in adults. Doctors use strong medicine (chemotherapy) and special rays (radiation therapy) to treat it. However, 80-90% of patients see the cancer come back, and...