Subventions financées

Women have a higher lifetime risk of Alzheimer’s disease (AD), possibly due to female-specific factors like menopause and pregnancy history.

The Challenge: Current therapies for treating a number of mental health disorders – depression, anxiety,
and PTSD, among them – adequately treat only a small fraction of afflicted patients.

This project explores how people living with dementia and their caregivers create clever do-it-yourself (DIY) solutions to make everyday tasks at home easier and safer.

Apathy (reduced goal-directed behaviour) is common in persons with dementia and is associated with lower quality of life, increased dependence and faster decline.

“Vascular pathology, such as loss of neurovascular coupling and disruption of the blood-brain barrier (BBB), has been documented in Huntington’s disease (HD).

"Antisense oligonucleotides (ASOs) are synthetic single-stranded DNA/RNA that are useful in the targeting of mRNA sequences."

One in five older adults with dementia is hospitalized each year.

Psychedelic drugs, known for their profound effects on perception, are showing promise as rapid and long-lasting treatments for depression.

We propose to develop chemically defined synthetic extracellular matrices to support neural cells in longterm stable cell culture.

One of the key processes driving Alzheimer’s Disease is inflammation in the brain, the severity of which may predict the severity of disease.