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835 résultats trouvés

A combined in-vivo ex-vivo approach to investigate imaging biomarkers in ALS diagnosis and aetiology

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder with no known cure, leading to progressive loss of motor function and ultimately death.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Neurodégénérescence
Concours
Prix Rising Stars pour les stagiaires
Province
Québec
DATE DE DÉBUT
2024

Sex Differences in Association between hypertension and Cognitive Health: The Role of Small Vessel Disease

The understanding of the factors responsible for the increased risk of cognitive problems in women remains limited.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Système nerveux central
Province
Québec
DATE DE DÉBUT
2024

Predicting Behavioural Deficits and Creating Biomarkers After Repeated Sub-concussive Injury

Concussions frequently occur worldwide, with a subset of patients experiencing lasting symptoms impacting their quality of life.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Blessures
Concours
Prix Rising Stars pour les stagiaires
Province
Ontario
DATE DE DÉBUT
2024

The application of 3D models to assess the role of microglia in neurodegenerative disorders

Challenge: Alzheimer’s disease (AD) is characterized by a decline in cognitive function, yet it is now widely acknowledged that as the disease advances, dopaminergic neurons in the midbrain become particularly vulnerable, leading to non-cognitive symptoms such as motor dysfunction.


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Neurodégénérescence
Concours
CQDM - Brain Canada - Quantum Leap
Province
Québec
DATE DE DÉBUT
2024

Relevance of stress granule dynamics to ALS pathogenesis in vivo

Amyotrophic lateral sclerosis (ALS) also known as Lou Gehrig’s Disease, is a neurodegenerative disease for which there is no effective treatment.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurodégénérescence
Province
Québec
DATE DE DÉBUT
2024

Investigating inhibition of TDP-43 propagation as a therapeutic strategy for ALS

It is not known why ALS is a rapidly progressing disease.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurodégénérescence
Province
Québec
DATE DE DÉBUT
2024

Targeting KCC2 for rescuing functional impairments in Alzheimer’s disease

Within the brain, cells communicate by sending signals that either enhance or dampen the activity of other cells.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Neurodégénérescence
Province
Québec
DATE DE DÉBUT
2024

Using neuroimaging to predict recovery from acute brain injury

When a person suffers a severe brain injury, whether from an accident, stroke, or infection, clinicians struggle to predict if they will recover.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Concours
Prix Rising Stars pour les stagiaires
Province
Ontario
DATE DE DÉBUT
2024

Correlating quaternary structure of pathological protein aggregates with phenotypic presentation of ALS

Amyotrophic lateral sclerosis (ALS) is a disease of progressive weakness that leads to death within a few years of onset.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurodégénérescence
Province
Québec
DATE DE DÉBUT
2024

Impact of 2-hydroxyglutarate-induced astrocytes reactivity in low-grade glioma progression and recurrence

Mutations in the metabolic enzymes are commonly observed in brain cancers.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Le cancer
Concours
Subventions de fonctionnement du CRS
Province
Québec
DATE DE DÉBUT
2024