Subventions financées

Systems neuroscience owes much of its success to an empirical tradition of using simplified laboratory settings that carefully control sensory stimuli, motor responses, or other task-relevant variables in order to identify the neural mechanisms underlying different behavioral functions.

A type of brain cancers called “diffuse gliomas” currently lacks effective treatments.

A hallmark and the earliest event taking place in ALS is the denervation of neuromuscular junctions (NMJs), which results in muscle weakness and paralysis.

Neuromuscular diseases (NMDs) are rare conditions that affect nerves and muscles.

Glioblastoma (GBM) is the most common and deadly adult brain cancer.

Palliative care (PC) is an area of medicine that focuses on symptom control and quality of life of patients with life-limiting illnesses and their families.

CAR-T therapies have delivered promising results for certain hematological cancers but remain largely ineffective for solid tumours with failure nodes including complex and hostile tumor microenvironments and the lack of adapted technological tools.

Challenge: ALS (amyotrophic lateral sclerosis) is an incurable and invariably fatal motor neuron (MN) disease.

Glioblastoma is one of the most aggressive brain cancers, with very few treatment options and a poor survival rate.

Challenge: Delivery of therapeutic proteins to the brain has been a longstanding barrier to CNS drug
development.