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3 résultats trouvés

Rebalancing Cortical Circuits: Restoring Inhibition to Halt Neurodegeneration

Frontotemporal dementia (FTD) is a progressive brain disorder that primarily affects thinking, behavior, and social interactions. It is the most common form of dementia in adults under 65 and places a heavy burden on patients, families, and healthcare systems. Despite this, we still lack effective treatments, partly because the brain mechanisms that cause symptoms are poorly understood.

TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Neurodégénérescence
Concours
Les futurs leaders de la recherche sur le cerveau au Canada
Province
Québec
DATE DE DÉBUT
2026

Therapeutic validation of gene-based strategies aimed at restoring neuronal KCC2 in ALS

An imbalance between excitation and inhibition is one of the earliest detectable features of amyotrophic lateral sclerosis (ALS).


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Neurodégénérescence
Province
Québec
DATE DE DÉBUT
2024

Examining the role of KCC2 in maintaining the balance between excitation and inhibition in ALS

Each muscle in the body receives electrical signals through motor neurons that will stimulate it to contract.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Neurodégénérescence
Province
Québec
DATE DE DÉBUT
2018