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2 résultats trouvés

Selective knockdown of misfolded SOD1 as a therapy for amyotrophic lateral sclerosis

In some cases of ALS, it is clear that specific inherited genetic changes (called mutations) can not only cause the disease, but can do so by creating a protein (the end product of genes that actually does a function in our cells) that has an abnormal, toxic function resulting in motor neuron degeneration.

Projet terminé Voir le projet et les chercheurs
TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurodégénérescence
Province
Manitoba
DATE DE DÉBUT
2015

Brain channelopathies: target validation and novel therapeutic strategies

The entry of calcium ions into cells is mediated by a class of protein (called calcium  channels) that responds to electrical signals by opening of a calcium-selective pore.

Projet en cours Voir le projet et les chercheurs
TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurotechnologie
Province
Colombie-Britannique
DATE DE DÉBUT
2014