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13 résultats trouvés

Investigating the templated propagation and impact of pathogenic FUS in hiPSCs-derived cerebral organoids

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that affects the human motor system, leading to muscle weakness and ultimately paralysis.


Domaine de recherche
Neurodégénérescence
Province
Québec
DATE DE DÉBUT
2025

Investigating inhibition of TDP-43 propagation as a therapeutic strategy for ALS

It is not known why ALS is a rapidly progressing disease.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurodégénérescence
Province
Québec
DATE DE DÉBUT
2024

Personalized medicine for Bipolar disorder: clinical lithium response as a guide to mode of action and biomarker discovery using human neurons and biofluids

Bipolar Disorder (BD) is a chronic psychiatric illness, ranking in the top 10 causes of disability and mortality worldwide, due to suicide and cardiovascular death.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Santé mentale
Province
Québec
DATE DE DÉBUT
2022

The Neuro’s Virtual Integrated Patient Platform

Patients with neurological disease are understandably frustrated by the lack of meaningful pharmacological treatments for even comparatively common pathologies such as Parkinson’s Disease.


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Multiple
Province
Québec
DATE DE DÉBUT
2022

Canadian Open Parkinson Network (C-OPN)

The Canadian Open Parkinson Network, or C-OPN, is a national network that unites researchers, physicians and patients across Canada to study Parkinson’s disease (PD).


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Neurodégénérescence
Concours
Autres
Province
Alberta
DATE DE DÉBUT
2018

A patient-derived iPSC platform of disease relevant cell models for biological studies

One of the greatest advancements in science over the past 10 years is the development of induced pluripotent stem cells (iPSCs).


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurodégénérescence
Province
Québec
DATE DE DÉBUT
2017

Montreal integrated neuropsychiatric cohort: Identifying subtypes of Autism and Schizophrenia integrating genomics, endophenotypes, and cohorts of high-risk genetic variants

Autism spectrum disorders (ASD) and schizophrenia (SZ) are two psychiatric conditions that affect approximately 2% of the general population. Genetic studies have identified mutations in hundreds of genes associated with ASD and SZ.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Multiple
Province
Québec
DATE DE DÉBUT
2017

Project MinE

Project MinE is a multi-national initiative with currently participating countries.


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Neurodégénérescence
Concours
Autres
Province
Québec
DATE DE DÉBUT
2017

Canadian Open Neuroscience Platform (CONP)

The Canadian Open Neuroscience Platform (CONP) is a national platform for open sharing of neuroscience research data and brings together many of the country’s leading scientists in basic and clinical neuroscience to form an interactive network of collaborations in brain research


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Neurotechnologie
Concours
Neuroscience ouverte/partage de données PSG
Province
Québec
DATE DE DÉBUT
2017

A Patient-Derived hiPSC Neuronal Platform for Drug Discovery in Parkinson’s Disease and Amyotrophic Lateral Sclerosis

Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are two of the most common and devastating neurodegenerative diseases, affecting more than 2% of the population over the age of 65.


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Neurodégénérescence
Concours
CQDM - Brain Canada - Pleins feux sur le cerveau
Province
Québec
DATE DE DÉBUT
2016