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774 results found

Tanycytic structural plasticity in circumventricular organs underlies homeostatic brain-body communication

  • Grant Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Metabolic syndrome is a group of risk factors (obesity, hypertension, high fasting blood sugar, and high levels of triglycerides) that increase the risk of type 2 diabetes and cardiovascular diseases. Over 20% of adult Canadians suffer from metabolic syndrome (40% in adults over 60 years old), and effective treatments are…

Laminar regulation of hemodynamics in primary auditory cortex

  • Grant Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Brain disorders and disease represent an immense societal burden and the leading cost to the Canadian health care system. Although research in animal models has led to major advances in our understanding of brain function and dysfunction at the cellular level, a major challenge remains bridging these findings from animals…

A Human System to study Immune-Ependymal Cell Relationships

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Multiple Sclerosis

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Ependymal cells are a largely understudied barrier cell type in the brain that provide a wall between brain tissue and brain fluid (cerebral spinal fluid, CSF), playing an important role in regulating fluid balance. These cells become dysfunctional in many brain diseases and this dysfunction contributes to neurodegeneration that occurs…

Detection of tandem repeat expansion in neurological disorders

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

In the past decade, rapid development of software has allowed detection of a wide variety of genetic risk factors in brain disorders. It has improved clinical diagnosis and gene discovery for numerous human brain disorders. However, the casual genetic risk factors identified so far generally confer less risk than expected…

Neural predictors of theta burst stimulation

  • Grant Type

    Capacity building grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Ontario

  • Start Date

    2021

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

In Canada, 1 in 20 people live with depression. Substantial efforts have been made over the years to develop new treatments to enhance therapeutic options. One effective alternative to medication is theta burst stimulation (TBS). This technique uses magnetic fields applied to the outside of the head to modulate brain…