Directory of funded grants

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774 results found

Multi-scale analyses of brain connectivity and dynamics in autism spectrum conditions

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Autism spectrum disorder (ASD) affects approximately 1 in 70 children and is associated to a considerable burden for affected individuals, their families, and health care at large. As ASD remains not very well understood from a neuroscientific perspective, we currently lack diagnostic and intervention approaches that target potential biological mechanisms.…

Project Ongoing

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2019 Dr. Hubert van Tol Travel Fellowship

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Competition

    Dr. Hubert van Tol Travel Fellowship

  • Province

    Québec

  • Start Date

    2019

  • Total Grant Amount

    $4,165

  • Health Canada Contribution

    $2,082

Project Overview

I was selected to present a poster during one of the 2 poster sessions. The project I presented was aimed at deciphering the molecular function of the Boc receptor in axon guidance. This receptor is necessary for the activation of Shh signaling but how Boc receptor binding to Shh triggers…

Project Complete

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Development of a high throughput 3D microphysiologicalplatform for rapid automated assessment of human brain organoids response to drugs targeting neurological disorders

  • Grant Type

    Platform grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Parkinson's,  Alzheimer’s

  • Competition

    CQDM - Brain Canada - Quantum Leap

  • Province

    Québec

  • Start Date

    2020

  • Total Grant Amount

    $1,600,000

  • Health Canada Contribution

    $800,000

Project Overview

Alzheimer's disease (AD) and Parkinson’s disease (PD) are the most common and devastating neurological diseases, with over 750,000 AD patients and over 100,000 PD patients in Canada. Drug development remains a slow, expensive and inefficient process. The biopharmaceutical industries need alternative models that better predict the human response to drugs…

Project Complete

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Disrupted SUMOylation facilitates rogue TDP-43 in ALS

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    ALS Canada – Brain Canada Trainee Program 2019

  • Province

    Ontario

  • Start Date

    2019

  • Total Grant Amount

    $75,000

  • Health Canada Contribution

    $37,500

Project Overview

Proteins are large molecules that play many essential roles in the body. They do most of the work inside cells and are necessary for the structure, function and regulation of all tissues and organs. TDP-43 is a protein that is usually found inside the cell nucleus. However, in most people…

Project Complete

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Biological and Pathological relevance of hnRNP A1B; An alternative splice variant of TDP-43

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    ALS Canada – Brain Canada Trainee Program 2019

  • Province

    Québec

  • Start Date

    2019

  • Total Grant Amount

    $75,000

  • Health Canada Contribution

    $37,500

Project Overview

In 97 per cent of ALS cases and nearly half of cases of frontotemporal dementia, the TDP-43 protein is misplaced to an area outside the cell nucleus of the motor neuron called the cytoplasm. The mislocated TDP-43 may be toxic to motor neurons because it aggregates in the cytoplasm, or…

Project Complete

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