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The Experimental Imaging Centre: a Local Brain Canada Platform for Preclinical MR Neuroimaging
Project Overview
The Experimental Imaging Centre Brain Canada Platform provides state of the art pre-clinical imaging to the neuroscience research community. The core technology is a 9.4T MRI with associated animal care and physiological monitoring aimed at rat and mouse models of human neuropathology. MRI has evolved over the past decades as…
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See the project and researchersThe Ontario Brain Epigenomics Platform
Project Overview
One of the frontiers in neuroscience is to understand the molecular dynamics of the brain functions. In addition to genetic and environmental modulation, the brain is also controlled by epigenetic mechanisms. These are chemical modifications of our genetic template that regulate gene activity in response to internal or external cues.…
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See the project and researchersHuman inducible pluripotent stem cells (iPSC) platform
Project Overview
Studies of genetic disorders are limited because of the lack of appropriate tissue samples from patients. A promising avenue to overcome this deficit is the recently described method of converting adult cells into inducible pluripotent stem cells (iPSC)1, and differentiating them into desired cell types such as various types of…
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See the project and researchersManitoba Neuroimaging Platform
Project Overview
Complex research questions in neurology are often most effectively addressed by monitoring brain structure and function in human patients and live animals in experimental disease models. Recent advances in radiology, computational analysis and medical physics have made it possible to accomplish this like never before. Despite this, research is hindered…
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See the project and researchersRegeneration Unit in Neurology: A platform for research and training in advanced microscopy and behavioural approaches
Project Overview
The Regeneration Unit in Neurobiology (RUN) Core facility is a purpose-built centre specializing in state of the art microscopic imaging of cells and tissue, as well as sophisticated behavioural analysis of laboratory rodents. Training, assistance, advice, and scientific consultation is available through our area managers, Dr. Simon Spanswick and Dr.…