Directory of funded grants

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799 results found

Targeting the telomere maintenance pathway for cancer diagnostics and therapeutics.

  • Grant Type

    Team grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Canadian Cancer Society Impact Grants

  • Province

    Ontario

  • Start Date

    2015

  • Total Grant Amount

    $1,249,765

  • Health Canada Contribution

    $624,883

Project Overview

Cancer can exhibit relentless growth and relapse because of the enhanced protection of its chromosome ends. Dr. Uri Tabori is a world expert in telomeres – the protective caps at the ends of DNA. Dr. Tabori has discovered that telomeres are maintained by a section of DNA called THOR. THOR…

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Molecular heterogeneity drives the clinical behaviour of childhood medulloblastoma

  • Grant Type

    Team grants

  • Area of research

    Cancer

  • Disease Area

    Brain Cancer

  • Competition

    Canadian Cancer Society Impact Grants

  • Province

    Ontario

  • Start Date

    2015

  • Total Grant Amount

    $1,249,880

  • Health Canada Contribution

    $624,940

Project Overview

Brain cancer is the most common type of solid cancer in children in Canada, and medulloblastoma is the most common malignant brain cancer of childhood.  Children diagnosed with medulloblastoma are often left with long-term effects from the intensive treatment. Dr. Taylor is studying how different medulloblastomas vary one from another…

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Novel Retinal Biomarkers for Alzheimer’s Disease

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    BC Alzheimer's Research Award Program

  • Province

    British Columbia

  • Start Date

    2015

  • Total Grant Amount

    $1,406,836

  • Health Canada Contribution

    $703,418

Project Overview

Individuals with Alzheimer’s suffer severe memory loss over time, and eventually are completely dependent on caregivers. Age is a significant risk factor, and the longer we live, the higher the chances of getting Alzheimer’s. Detecting the beginning of Alzheimer’s in an individual’s brain in the early stages is difficult as…

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Targeting Amyloid Propagation in Alzheimer Disease: Structures, Immunology and Extracellular Vesicle Topology

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    BC Alzheimer's Research Award Program

  • Province

    British Columbia

  • Start Date

    2015

  • Total Grant Amount

    $1,406,191

  • Health Canada Contribution

    $703,096

Project Overview

A treatment or prevention of Alzheimer's disease is a top priority for medical science. Small aggregates of the protein amyloid-beta (A-beta), called oligomers, have been identified as being the primary cause of brain cell death in Alzheimer’s disease. However, there are many different subtypes of amyloid-beta oligomers and the specific…

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Locally produced brain insulin in memory and Alzheimer’s disease: A multi-disciplinary approach to a key question

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    BC Alzheimer's Research Award Program

  • Province

    British Columbia

  • Start Date

    2015

  • Total Grant Amount

    $987,000

  • Health Canada Contribution

    $493,500

Project Overview

One percent of Alzheimer’s disease is the early-onset type that runs in families. Extensive studies of these ultra-rare forms of Alzheimer’s disease have revealed the genes that cause them. On the other hand, the most common forms of Alzheimer’s disease are surprisingly understudied and poorly understood at the level required…

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