720 results found
Characterization and modulation of the endocannabinoid system for treating Fragile X Syndrome
Project Overview
Fragile X syndrome (FXS) is the first inherited cause of intellectual disability and one of the most prevalent causes of autism spectrum disorders. Individuals with FXS do not produce a protein named FMRP. The absence of FMRP results in abnormal brain development and impaired synaptic transmission, which is the mechanism…
Project Ongoing
See the project and researchers2024 Dr. Hubert van Tol Travel Fellowship
Project Overview
Alison Wilson, a Master's Student at the University of Calgary, aims to use magnetic resonance spectroscopy to investigate the pathophysiology of chronic post-traumatic headache. Alison used the Dr. Hubert van Tol Travel Fellowship to attend the EDITINGSCHOOL and Symposium for GABA and Advanced Magnetic Resonance Spectroscopy in Playa Del Carmen,…
Project Ongoing
See the project and researchersThe Impact of Paediatric Brain Tumor Treatment on Structural and Functional Brain Connectivity
Project Overview
Thanks to advances in cancer treatments, more than 80% of children treated for brain tumors now survive at least five years after their diagnosis. However, these treatments can often harm the brain, affecting both its structure and function. The brain's structure, particularly the white matter pathways that connect different regions,…
Project Ongoing
See the project and researchersDeveloping a “one-two punch” treatment paradigm for targeting glioblastoma
Project Overview
By profiling the protein expression signatures of multiple patient-derived glioblastoma cell lines, we recently identified a major signalling pathway involved in glioblastoma cell migration. Excitingly, we showed that chemical inhibition of a key protein involved in regulating this pathway significantly reduced the infiltration of three glioblastoma cell lines. While inhibiting…
Project Ongoing
See the project and researchersAccelerating the Reach of the Driving and Dementia Roadmap
Project Overview
This project focuses on accelerating awareness about the importance of the issue of driving cessation by promoting the uptake of the Driving and Dementia Roadmap (DDR). The DDR is an online educational resource (toolkit) comprised of evidence-based information, resources and tools aimed at supporting people with dementia, family, friends, carers…