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556 results found

Microbiota-Microglia Interactions in Pediatric Inflammatory Bowel Disease

  • Program Type

    Capacity building grants

  • Area of research

    Mental Health

  • Disease Area

    Mental illness

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    British Columbia

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Despite the recent advances in our understanding between the connection between the microbes living in the gut and our mental health, there remains a wide knowledge gap in understanding how the brain is negatively impacted in disorders with inflammation of the gut. This is particularly important in the case of…

Remote Ischemic Preconditioning to promote CNS remyelination

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Multiple Sclerosis

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Alberta

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

In Multiple Sclerosis (MS), new brain lesions appear because of inflammation and loss of myelin (the structure covering nerves). MS treatments stop inflammation, but can´t repair the damage already done. Repairing myelin might be an effective treatment in MS, but there are no medications available that do this. Our own…

Magnetic resonance imaging to compare the abilities of non-selective and selective huntingtin suppression technologies to prevent brain pathology in Huntington disease

  • Program Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Newfoundland and Labrador

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Huntington disease (HD) is an inherited disorder that causes brain cells to die and impacts approximately 1 in 7000 Canadians. A person with HD experiences worsening psychiatric, motor, and memory impairments. While there is still no cure for HD, gene therapies have shown promise and entered clinical trials with the…

Representation of decision variables by catecholamines during learning

  • Program Type

    Capacity building grants

  • Area of research

    Cognition

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Our ability to learn is directly proportional to our ability to detect the difference between a prediction and its outcome. Reinforcement learning theories, which are widely used in neuroscience and machine learning, are based on this idea that learning only happens when a context falsely predicts an outcome, otherwise learning…

Deep neural networks applied to interictal EEG to improve the diagnosis of epilepsy

  • Program Type

    Capacity building grants

  • Area of research

    Seizure

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2022

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Epilepsy is a debilitating disease affecting 1% of the world’s population. It is characterized by an enduring propensity to recurring seizures. One of the cornerstones of the diagnosis and management of epilepsy is the electroencephalogram (EEG). The EEG is a recording of the brain’s electrical activity, typically for 30-minutes, and…