Directory of funded grants

Developing a digital signature of care-related activities and burden

Project Overview

We propose to develop a digital signature that identifies the level of care partner burden associated with person living with dementia (PLWD)/care partner dyads living in the community. This project will use longitudinal data collected in studies using the Collaborative Aging Research Using Technology (CART) Initiative technology platform with care…

Using mobile technology to inform driving decision-making in dementia

Project Overview

A major challenge in dementia care is determining the point at which driving becomes significantly compromised for people with dementia (PWD). Although physicians are expected to play a role in the driving decision-making process, many are reluctant to address this topic. Physicians typically rely on cognitive tests to assess fitness-to-drive…

Patient-reported outcome measures for social robots in dementia care

Project Overview

Improving independence and quality of life for persons living with dementia (PLWD) and their care partners can be realized by complementing human care with robotic assistive technologies. Social robots are promising in their potential to support the cognitive health of older adults and are already being deployed in many dementia-specific…

Mind Over Matter Magazine (Volume 15)

Loss of C9orf72 disrupts nucleoporins and contributes to TDP-43 mislocalization

Project Overview

Subcellular compartmentalization between the nucleus and cytoplasm is primarily governed by two systems; 1) active nucleocytoplasmic transport (NCT) regulated by Ran-GTPase and involving nuclear transport receptors such as Importin β-1, and 2) macromolecular nuclear pore complexes (NPCs), comprised of >30 nucleoporin (Nups) embedded in the nuclear envelope. FG-Nups, the largest…