Directory of funded grants

Filter by

676 results found

Cortical GABAergic interneurons migration impairment in genetic epileptic encephalopathies

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Brain Injury

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Québec

  • Start Date

    2018

  • Total Grant Amount

    $110,000

  • Health Canada Contribution

    $55,000

Project Overview

Dr. Eid will test the hypothesis that the Trio gene is a central regulator of the development and maturation of cortical interneurons (INs) and that its loss underlies some genetic forms of epileptic encephalopathies (EE) by disrupting cortical network development and function. Her research combines state-of-the art approaches in genetics…

Project Complete

See the project and researchers

In utero exposure to glucocorticoids in humans and an animal model: Epigenetic and transcriptional signatures

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Mental illness

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Ontario

  • Start Date

    2018

  • Total Grant Amount

    $40,000

  • Health Canada Contribution

    $20,000

Project Overview

Dr. Sasaki research aims to (1) determine the mechanisms by which maternal synthetic glucocorticoids (sGC) modifies gene networks in a preclinical guinea pig model and (2) determine the mechanism by which a single maternal treatment of sGC modifies gene networks in human cord blood at term deliveries. To date, there…

Project Complete

See the project and researchers

Effects of Sex Hormone Therapy on Brain Development in Adolescents Experiencing Gender Dysphoria: A Magnetic Resonance Imaging Study

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Other

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Ontario

  • Start Date

    2018

  • Total Grant Amount

    $110,000

  • Health Canada Contribution

    $55,000

Project Overview

Adolescence is a time of rapid brain maturation that is partly influenced by sex hormones. In this project, magnetic resonance imaging will be used to assess the influence of sex hormones on brain structure and function. Malvina Skorska will examine how the brain structure and function of adolescents who experience…

Project Complete

See the project and researchers

Brain-Computer Interface Integrated Augmentative and Alternative Communication

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Other

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    Ontario

  • Start Date

    2018

  • Total Grant Amount

    $70,000

  • Health Canada Contribution

    $35,000

Project Overview

The primary objective of Ms. Shea's research is to investigate an optimized integration of event related potentials (ERPs) as a means to augment assistive communication devices. Words, chosen through contextual constraints and rapidly presented to individuals offer superior communication efficiency over independent sequential letter selection. During the rapid presentation of…

Project Complete

See the project and researchers

CRISPR/Cas9-Mediated Gene Therapy to Correct Aniridia in a Mouse Model

  • Grant Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Brain Canada - Kids Brain Health Network Training Awards

  • Province

    British Columbia

  • Start Date

    2018

  • Total Grant Amount

    $60,000

  • Health Canada Contribution

    $30,000

Project Overview

Ms. Zeinab Mohanna's research will test the hypothesis that CRISPR/Cas9-mediated genome editing can increase the expression of PAX6 protein, improve the function of the neural and other tissues of the eye, and ultimately rescue the mutant phenotype in the mouse model of aniridia. Rare genetic diseases create a burden on…

Project Complete

See the project and researchers