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A Randomized Sham-Controlled Trial of Accelerated Intermittent Theta Burst Stimulation for Treatment Resistant Depression
https://braincanada.ca/fr/subventions-financées/a-randomized-sham-controlled-trial-of-accelerated-intermittent-theta-burst-stimulation-for-treatment-resistant-depressionBy 2050, over 1 million Canadians will suffer from depression; many of whom will not respond to traditional antidepressant medication, known to as treatment resistant depression (TRD). Project Overview By 2050, over 1 million Canadians will suffer from depression; many of whom will not respond to...
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A research platform to study animal and human cellular models of neurological disorders
https://braincanada.ca/fr/subventions-financées/a-research-platform-to-study-animal-and-human-cellular-models-of-neurological-disordersNeurological diseases including neurodegenerative, neurodevelopmental, and psychiatric disorders are collectively one of the leading causes of disability to the Canadian population. Project Overview Neurological diseases including neurodegenerative, neurodevelopmental, and psychiatric disorders are...
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A sustainable ecosystem of care for women with traumatic brain injury following intimate partner violence: First steps.
https://braincanada.ca/fr/subventions-financées/a-sustainable-ecosystem-of-care-for-women-with-traumatic-brain-injury-following-intimate-partner-violence-first-stepsWomen victims of intimate partner violence (IPV) are at high risk of traumatic brain injury (TBI). As many as 75% are thought to have sustained a TBI, though most remain undiagnosed and untreated, but nonetheless live with its lasting effects. Project Overview Women victims of intimate partner...
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A “tipping point” neuron type driving Alzheimer’s Disease progression
https://braincanada.ca/fr/subventions-financées/a-tipping-point-neuron-type-driving-alzheimer-s-disease-progressionAlzheimer’s Disease (AD) is characterized by dysregulation of neurons involved in memory, which is believed to be caused by the production of an agent termed “amyloid beta”. Project Overview Alzheimer’s Disease (AD) is characterized by dysregulation of neurons involved in memory, which is believed...
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A unifying approach to treat multisystem proteinopathy and ALS using noninvasive novel ASO delivery
https://braincanada.ca/fr/subventions-financées/a-unifying-approach-to-treat-multisystem-proteinopathy-and-als-using-noninvasive-novel-aso-deliveryMultisystem proteinopathy (MSP) is a devastating rare disease described by a cluster of diseases that affect the brain, bone, and muscle. Project Overview Multisystem proteinopathy (MSP) is a devastating rare disease described by a cluster of diseases that affect the brain, bone, and muscle....
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A universal platform for high volume genetic modifier testing in Tauopathy
https://braincanada.ca/fr/subventions-financées/a-universal-platform-for-high-volume-genetic-modifier-testing-in-tauopathyGenetic testing shows that the Tau gene can often carry changes (DNA mutations) in people with dementia, and also in people who are not yet diagnosed with dementia. Project Overview Genetic testing shows that the Tau gene can often carry changes (DNA mutations) in people with dementia, and also in...
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Aberrant tRNA function exacerbates TDP-43 misfolding and toxicity in cellular models of ALS
https://braincanada.ca/fr/subventions-financées/aberrant-trna-function-exacerbates-tdp-43-misfolding-and-toxicity-in-cellular-models-of-alsAberrant tRNA processing and function has the capacity to exacerbate misfolding of ALS-associated proteins and the ensuing toxicity. Project Overview Aberrant tRNA processing and function has the capacity to exacerbate misfolding of ALS-associated proteins and the ensuing toxicity. tRNAs mainly...
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Accelerating implementation of Canada’s first national Pediatric Pain Standard: Enhancing equitable care for children with neurodevelopmental disabilities in hospital settings
https://braincanada.ca/fr/subventions-financées/accelerating-implementation-of-canada-s-first-national-pediatric-pain-standard-enhancing-equitable-care-for-children-with-neurodevelopmental-disabilities-in-hospital-settingsCanada is a world leader in children’s pain research and effective treatments exist, yet Canadian children continue to experience undertreated and preventable pain. Project Overview Canada is a world leader in children’s pain research and effective treatments exist, yet Canadian children continue...
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Accelerating the Integration of Be EPIC-VR in Dementia Care
https://braincanada.ca/fr/subventions-financées/accelerating-the-integration-of-be-epic-vr-in-dementia-carePersonal support workers provide the most formal care to people living with dementia. Project Overview Personal support workers provide the most formal care to people living with dementia. Their formal training often does not address complex dementia-related communication impairments and responsive...
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Accelerating the Reach of the Driving and Dementia Roadmap
https://braincanada.ca/fr/subventions-financées/accelerating-the-reach-of-the-driving-and-dementia-roadmapThis project focuses on accelerating awareness about the importance of the issue of driving cessation by promoting the uptake of the Driving and Dementia Roadmap (DDR). Project Overview This project focuses on accelerating awareness about the importance of the issue of driving cessation by...