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A National biobank and database for patients with traumatic brain injury
https://braincanada.ca/fr/subventions-financées/a-national-biobank-and-database-for-patients-with-traumatic-brain-injuryTraumatic brain injury is the leading cause of death and disability in children and young adults in Canada. Project Overview Traumatic brain injury is the leading cause of death and disability in children and young adults in Canada. Despite huge developments in basic neuroscience, no new therapies...
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A national coordinating neuroinformatics framework for autism and related conditions
https://braincanada.ca/fr/subventions-financées/a-national-coordinating-neuroinformatics-framework-for-autism-and-related-conditionsNew approaches in neurodevelopmental research increasingly seek to integrate enormous amounts of data through sophisticated informatics so as to determine the relationship between genotype and phenotypes, both structural and functional, as they change over time during development. Project...
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A neurorehabilitation platform to discover and develop neuroprosthetic therapies in the rodent
https://braincanada.ca/fr/subventions-financées/a-neurorehabilitation-platform-to-discover-and-develop-neuroprosthetic-therapies-in-the-rodentRecovery of movement after a spinal cord injury starts in the brain. Project Overview Recovery of movement after a spinal cord injury starts in the brain. Two-thirds of spinal cord injuries are not complete, meaning some connections and voluntary movement remain. In such cases, the nervous system...
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A novel immunotherapy based on genetically modified hematopoietic stem cells as a new hope for treating glioblastoma, an aggressive cancerous tumor of the brain
https://braincanada.ca/fr/subventions-financées/a-novel-immunotherapy-based-on-genetically-modified-hematopoietic-stem-cells-as-a-new-hope-for-treating-glioblastoma-an-aggressive-cancerous-tumor-of-the-brainLed by Dr. Elie Haddad from CHU Sainte-Justine in collaboration with Immugenia, this project includes an inter-provincial research collaboration Project Overview Led by Dr. Elie Haddad from CHU Sainte-Justine in collaboration with Immugenia, this project includes an inter-provincial research...
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A Novel Microfluidic Platform for Investigating Axonal Sprouting in Motor Neurons
https://braincanada.ca/fr/subventions-financées/a-novel-microfluidic-platform-for-investigating-axonal-sprouting-in-motor-neuronsMotor neurons are extremely complex cells. Not only do they have an intricate set of inner workings, but they have a long wire-like portion called an axon that connects the central nervous system to muscles called an axon. Project Overview Motor neurons are extremely complex cells. Not only do they...
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A Novel Zebrafish-Based Platform for Anticonvulsant Drug Development
https://braincanada.ca/fr/subventions-financées/a-novel-zebrafish-based-platform-for-anticonvulsant-drug-developmentEpilepsy is a common neurological condition that affects 1-2% of the population. Project Overview Epilepsy is a common neurological condition that affects 1-2% of the population. Despite dozens of anticonvulsant medications, over a third of patients remain refractory to drugs and our goal is to...
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A Patient-Derived hiPSC Neuronal Platform for Drug Discovery in Parkinson’s Disease and Amyotrophic Lateral Sclerosis
https://braincanada.ca/fr/subventions-financées/a-patient-derived-hipsc-neuronal-platform-for-drug-discovery-in-parkinson-s-disease-and-amyotrophic-lateral-sclerosisParkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are two of the most common and devastating neurodegenerative diseases, affecting more than 2% of the population over the age of 65. Project Overview Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are two of the most...
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A patient-derived iPSC platform of disease relevant cell models for biological studies
https://braincanada.ca/fr/subventions-financées/a-patient-derived-ipsc-platform-of-disease-relevant-cell-models-for-biological-studiesOne of the greatest advancements in science over the past 10 years is the development of induced pluripotent stem cells (iPSCs). Project Overview One of the greatest advancements in science over the past 10 years is the development of induced pluripotent stem cells (iPSCs). These cells make it...
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A personalized medicine approach to better understand the biology of bipolar disorder
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/a-personalized-medicine-approach-to-better-understand-the-biology-of-bipolar-disorder -
A physiologic-to-tissue level approach to characterize the pathophysiology of hypoxic ischemic brain injury in humans.
https://braincanada.ca/fr/subventions-financées/a-physiologic-to-tissue-level-approach-to-characterize-the-pathophysiology-of-hypoxic-ischemic-brain-injury-in-humansDuring a cardiac arrest, when the heart stops beating, blood flow and the delivery of the oxygen to the brain stops. Project Overview During a cardiac arrest, when the heart stops beating, blood flow and the delivery of the oxygen to the brain stops. This lack of blood flow and oxygen leads to a...
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