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Characterizing the roles of synapse organizers in mediating synaptic function and brain-based diseases
https://braincanada.ca/fr/subventions-financées/characterizing-the-roles-of-synapse-organizers-in-mediating-synaptic-function-and-brain-based-diseasesThe human brain is made up of neural circuits that are thought to underlie all brain function. Project Overview The human brain is made up of neural circuits that are thought to underlie all brain function. These circuits are made up of contact points called synapses where individual nerve cells...
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Charlotte Manser transforme son deuil en espoir pour d’autres familles touchées par la SLA
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/charlotte-manser-transforme-son-chagrin-en-espoirRencontrez les étudiants à l'origine des bourses de stage SLA Canada - Cerveau Canada 2022. Charlotte Manser est la lauréate d'une bourse de stagiaire SLA Canada - Cerveau Canada 2022 d 'une valeur de 75 000 $. Étudiante au doctorat à l'Université d'Ottawa, elle étudie comment les gènes liés à la...
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Cholinergic & noradrenergic contributions to presymptomatic AD progression
https://braincanada.ca/fr/subventions-financées/cholinergic-noradrenergic-contributions-to-presymptomatic-ad-progressionThe development of approaches to aid early detection of the transition from healthy aging to mild cognitive impairment and Alzheimer’s disease (AD) is critically important for developing targeted strategies to halt or slow disease progression. Project Overview The development of approaches to aid...
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Cinq équipes dirigées par des Canadiens reçoivent des subventions internationales pour faire avancer la recherche sur la maladie d'Alzheimer et la démence
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/cinq-équipes-dirigées-par-des-canadiens-reçoivent-des-subventions-internationales-pour-faire-avancer-la-recherche-sur-la-maladie-d-alzheimer-et-la-démenceDe gauche à droite : Sylvain Baillet, James Carmichael, Shehroz Khan, Derya Sargin, et Nathan Spreng En collaboration avec l'Alzheimer's Association, Brain Canada finance cinq équipes de recherche afin de développer des données préliminaires et d'appliquer les connaissances aux domaines de...
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Circadian control of microglial activation in chronic pain states
https://braincanada.ca/fr/subventions-financées/circadian-control-of-microglial-activation-in-chronic-pain-statesCircadian, or 24-hour, rhythms control almost all biological systems in our bodies with sleep-wake cycles and body temperature control the best known examples. Project Overview Circadian, or 24-hour, rhythms control almost all biological systems in our bodies with sleep-wake cycles and body...
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Closed-loop deep brain stimulation using chronic intracranial cortical sensing to inform subcortical stimulation delivery
https://braincanada.ca/fr/subventions-financées/closed-loop-deep-brain-stimulation-using-chronic-intracranial-cortical-sensing-to-inform-subcortical-stimulation-deliveryMany people with Parkinson’s disease have trouble with freezing of gait (FoG), a symptom that causes them to stop walking unexpectedly and makes them more likely to fall. Project Overview Many people with Parkinson’s disease have trouble with freezing of gait (FoG), a symptom that causes them to...
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Co-clinical trials of autism in mice and humans
https://braincanada.ca/fr/subventions-financées/co-clinical-trials-of-autism-in-mice-and-humansAutism is a neuro-developmental disorder characterized by social/communication deficits and repetitive behaviours. Project Overview Autism is a neuro-developmental disorder characterized by social/communication deficits and repetitive behaviours. It is very heterogeneous, with over 250 genes...
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CODEX Trial
https://braincanada.ca/fr/subventions-financées/codex-trialEach year, over 312 million patients undergo surgery. Project Overview Each year, over 312 million patients undergo surgery. Anesthesia is a drug-induced reversible, comatose state that facilitates surgery. It is widely assumed cognition returns to baseline afterwards. Surgery and anesthesia...
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Cognition and Functional Specialization in Connectome-Based Neuromorphic Networks
https://braincanada.ca/fr/subventions-financées/cognition-and-functional-specialization-in-connectome-based-neuromorphic-networksHow does the wiring of the brain confer cognitive capacity? Project Overview How does the wiring of the brain confer cognitive capacity? Technological, analytic, and theoretical advances present a unique opportunity to reconstruct brain networks in individuals. At the same time, modern artificial...
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Cognitive Outcomes and Response/Remission Efficacy of Convulsive Therapies in Treatment Resistant Depression: The CORRECT-TRD Trial
https://braincanada.ca/fr/subventions-financées/cognitive-outcomes-and-response-remission-efficacy-of-convulsive-therapies-in-treatment-resistant-depression-the-correct-trd-trialMagnetic Seizure Therapy (MST) is a novel form of treatment that uses high intensity magnetic field pulses to stimulate the brain and induce a seizure as a therapeutic intervention for patients with depression resistant to antidepressant medication, known as Treatment Resistant Depression (TRD)....