-
Gagnants du C-OPN Data Challenge
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/gagnants-du-concours-de-données-de-l-opnBrain Canada et Parkinson Canada sont heureux d'annoncer les gagnants du défi de données du Réseau ouvert canadien Parkinson (ROCP). Cette opportunité de subvention de recherche, lancée et financée en partenariat entre Parkinson Canada et Brain Canada, a été conçue pour accélérer la recherche sur la...
-
Gangliosides in Huntington’s disease: from bench to clinics and back
https://braincanada.ca/fr/subventions-financées/gangliosides-in-huntington-s-disease-from-bench-to-clinics-and-backHuntington disease (HD) is an inherited disorder that causes progressive malfunctioning and death of parts of the brain that control movement, reasoning and emotions. Project Overview Huntington disease (HD) is an inherited disorder that causes progressive malfunctioning and death of parts of the...
-
Garden of Resilience: Stories of Disruption and Adaptation during the 21st Century
https://braincanada.ca/fr/subventions-financées/garden-of-resilience-stories-of-disruption-and-adaptation-during-the-21st-centuryIn the era of climate change-related disasters and a globally disruptive pandemic, people worldwide are grappling with the question of how to foster resilience. Project Overview In the era of climate change-related disasters and a globally disruptive pandemic, people worldwide are grappling with...
-
Generating expanded repeats in the C9ORF72 ortholog in zebrafish
https://braincanada.ca/fr/subventions-financées/generating-expanded-repeats-in-the-c9orf72-ortholog-in-zebrafishOver the past several years, zebrafish have proven to be a valuable model to study motor neuron degeneration and search for new treatments. Project Overview Over the past several years, zebrafish have proven to be a valuable model to study motor neuron degeneration and search for new treatments. To...
-
Genes involved in APP-mediated GLUT1 regulation
https://braincanada.ca/fr/subventions-financées/genes-involved-in-app-mediated-glut1-regulationAlzheimer’s disease is the most common form of dementia. Project Overview Alzheimer’s disease is the most common form of dementia. The brains of many of the patients are less well supplied with glucose (sugar), but not much research aims to understand why this happens. Further, a protein of central...
-
Genetic and therapeutic dependencies in SHH driven childhood medulloblastoma
https://braincanada.ca/fr/subventions-financées/genetic-and-therapeutic-dependencies-in-shh-driven-childhood-medulloblastomaMedulloblastoma is the most common malignant brain tumour of childhood, affecting 60-80 Canadian children per year. Project Overview Medulloblastoma is the most common malignant brain tumour of childhood, affecting 60-80 Canadian children per year. The treatment for medulloblastoma comprises...
-
Genomic markers of cerebral small vessel ischemia
https://braincanada.ca/fr/subventions-financées/genomic-markers-of-cerebral-small-vessel-ischemiaThe overall goal of this research program is to identify genomic markers that predict small vessel disease of the brain. Project Overview The overall goal of this research program is to identify genomic markers that predict small vessel disease of the brain. Specifically we will investigate...
-
Geometric Determinants of Hippocampal Spatial Encoding
https://braincanada.ca/fr/subventions-financées/geometric-determinants-of-hippocampal-spatial-encodingOur brains have their own GPS – the hippocampus, a region where special neurons, called ‘place cells’, help us navigate and store memories. Project Overview Our brains have their own GPS – the hippocampus, a region where special neurons, called ‘place cells’, help us navigate and store memories....
-
Gold and BBB Opening in ALS (The GOALS Trial): A Phase 2a, Open-label, Single-arm Clinical Trial of Oral CNM-Au8 Coupled with Primary Motor Cortex Blood Brain Barrier Opening Using Transcranial MR-guided Focused Ultrasound in Amyotrophic Lateral Sclerosis
https://braincanada.ca/fr/subventions-financées/gold-and-bbb-opening-in-als-the-goals-trial-a-phase-2a-open-label-single-arm-clinical-trial-of-oral-cnm-au8-coupled-with-primary-motor-cortex-blood-brain-barrier-opening-using-transcranial-mr-guided-focused-ultrasound-in-amyotrophic-lateral-sclerosisRationale: Mitochondrial dysfunction has been identified as a contributing factor for bioenergetic dysregulation and neurodegeneration in the motor cortex and spinal cord of patients with ALS. Project Overview Rationale: Mitochondrial dysfunction has been identified as a contributing factor for...
-
GPNMB CAR-T Cells as a Multi-Pronged Immunotherapeutic Approach for Glioblastoma
https://braincanada.ca/fr/subventions-financées/gpnmb-car-t-cells-as-a-multi-pronged-immunotherapeutic-approach-for-glioblastomaGlioblastoma (GBM) is the most common and deadly adult brain cancer. Project Overview Glioblastoma (GBM) is the most common and deadly adult brain cancer. GBM is particularly challenging because it contains many different cell types that help it grow and resist treatment, one of which are immune...