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Glioblastoma multiforme and high grade astrocytomas are aggressive brain tumors that are difficult to treat. Project Overview Glioblastoma multiforme and high grade astrocytomas are aggressive brain tumors that are difficult to treat. These tumors have genetic changes that affect their ability to...

This project will focus on unique roles of FUS (an ALS gene/protein) at the junction where neurons connect, called the synapse. Project Overview This project will focus on unique roles of FUS (an ALS gene/protein) at the junction where neurons connect, called the synapse. Most of the work done on...

In Canada, one individual suffers a stroke every seven minutes. Project Overview In Canada, one individual suffers a stroke every seven minutes. Of those who survive, roughly 30% will have aphasia, a difficulty speaking with- or understanding others. Aphasia can have a significant negative impact...

Our research program is centered on investigating the important contributions of metabolism to brain health. Project Overview Our research program is centered on investigating the important contributions of metabolism to brain health. It is generally well-accepted that proper nutrition is a major...

Apathy (reduced goal-directed behaviour) is common in persons with dementia and is associated with lower quality of life, increased dependence and faster decline. Project Overview Apathy (reduced goal-directed behaviour) is common in persons with dementia and is associated with lower quality of...

Despite the recent advances in our understanding between the connection between the microbes living in the gut and our mental health, there remains a wide knowledge gap in understanding how the brain is negatively impacted in disorders with inflammation of the gut. Project Overview Despite the...

Antibody (Ab)-based therapeutics are the fastest growing class of drugs, with approximately 60 approved molecules that represent a market of over $80B. Project Overview Antibody (Ab)-based therapeutics are the fastest growing class of drugs, with approximately 60 approved molecules that represent a...

Microglia, the brain’s resident immune cells, are vital for healthy brain function. Project Overview Microglia, the brain’s resident immune cells, are vital for healthy brain function. This is partially accomplished through their interactions with the primary brain cells, neurons, and those cells’...

Alzheimer’s disease (AD) is the most common form of dementia and 7th leading cause of death in North-America. Project Overview Alzheimer’s disease (AD) is the most common form of dementia and 7th leading cause of death in North-America. It affects memory, thinking and behavior, thus causing major...

Partners and Donors Women's Brain Health Initiative