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Two-thirds of individuals suffering from Alzheimer’s disease are women. Project Overview Two-thirds of individuals suffering from Alzheimer’s disease are women. The reason for women’s increased risk of Alzheimer’s disease is unknown. Menopause occurs when a decline in a hormone called estrogen...

Recherche de l'hormone leptine en tant que nouveau biomarqueur possible de la SLA grâce à une bourse de découverte "Dans notre projet, il existe une collaboration cruciale entre la recherche clinique et la recherche fondamentale Dr. Jasna Kriz Bien qu'un métabolisme rapide soit souvent considéré...

Neuromuscular diseases (NMDs) are rare conditions that affect nerves and muscles. Project Overview Neuromuscular diseases (NMDs) are rare conditions that affect nerves and muscles. These diseases can be complex and require significant healthcare resources, but because they are rare, there are many...

La Fondation Brain Canada investit dans des plateformes de recherche transformatrices à l’échelle du pays afin d’accélérer les découvertes en neurosciences et d’améliorer les perspectives pour les personnes vivant avec des troubles cérébraux. La présidente et chef de la direction de Brain Canada,...

Neuroinflammation has been implicated in a diverse array of degenerative conditions, ranging from Multiple Sclerosis  to  Alzheimer’s  disease. Project Overview Neuroinflammation has been implicated in a diverse array of degenerative conditions, ranging from Multiple Sclerosis  to  Alzheimer’s ...

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating neurodegenerative diseases which have overlap in pathological features and the genetic basis. Project Overview Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating...

Medulloblastoma (MB) is a brain cancer that affects children. Medulloblastoma (MB) is a brain cancer that affects children. Current treatment for MB leaves patients with debilitating brain issues. We found that aggressive MB have low activity of a process called nonsense mediated decay (NMD)....

Women have a higher lifetime risk of Alzheimer’s disease (AD), possibly due to female-specific factors like menopause and pregnancy history. Project Overview Women have a higher lifetime risk of Alzheimer’s disease (AD), possibly due to female-specific factors like menopause and pregnancy history....

TDP-43 is an essential DNA/RNA binding protein at the epicenter of Amyotrophic Lateral Sclerosis (ALS). Project Overview TDP-43 is an essential DNA/RNA binding protein at the epicenter of Amyotrophic Lateral Sclerosis (ALS). Nearly all cases of ALS present with TDP-43 pathology involving nuclear to...