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Functional investigation of a novel genetic player in brain development
https://braincanada.ca/fr/subventions-financées/functional-investigation-of-a-novel-genetic-player-in-brain-developmentThe human brain’s development relies on precisely coordinated genetic programs that ensure proper wiring and function. Project Overview The human brain’s development relies on precisely coordinated genetic programs that ensure proper wiring and function. When these processes go awry,...
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Futurs leaders canadiens de la recherche sur le cerveau – Subventions Momentum
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/bourses-d-encouragement-pour-les-futurs-leaders-de-la-recherche-canadienne-sur-le-cerveau-2Les subventions Momentum permettent aux anciens lauréats d’une subvention Futurs leaders canadiens de la recherche sur le cerveau de mettre à profit l’élan généré par leur financement de démarrage. Les subventions Momentum permettent aux anciens lauréats d’une subvention Futurs leaders canadiens de...
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Gagner la course contre la montre pour préserver le cerveau après un AVC
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/gagner-la-course-contre-la-montre-après-un-accident-vasculaire-cérébralUn groupe de médicaments appelés neuroprotecteurs suscite l’intérêt depuis de nombreuses années comme solution potentielle pour combler l’intervalle critique entre l’apparition des symptômes et l’administration des traitements définitifs. Comme leur nom l’indique, les neuroprotecteurs visent à...
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Gangliosides in Huntington’s disease: from bench to clinics and back
https://braincanada.ca/fr/subventions-financées/gangliosides-in-huntington-s-disease-from-bench-to-clinics-and-backHuntington disease (HD) is an inherited disorder that causes progressive malfunctioning and death of parts of the brain that control movement, reasoning and emotions. Project Overview Huntington disease (HD) is an inherited disorder that causes progressive malfunctioning and death of parts of the...
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Garden of Resilience: Stories of Disruption and Adaptation during the 21st Century
https://braincanada.ca/fr/subventions-financées/garden-of-resilience-stories-of-disruption-and-adaptation-during-the-21st-centuryIn the era of climate change-related disasters and a globally disruptive pandemic, people worldwide are grappling with the question of how to foster resilience. Project Overview In the era of climate change-related disasters and a globally disruptive pandemic, people worldwide are grappling with...
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Generating expanded repeats in the C9ORF72 ortholog in zebrafish
https://braincanada.ca/fr/subventions-financées/generating-expanded-repeats-in-the-c9orf72-ortholog-in-zebrafishOver the past several years, zebrafish have proven to be a valuable model to study motor neuron degeneration and search for new treatments. Project Overview Over the past several years, zebrafish have proven to be a valuable model to study motor neuron degeneration and search for new treatments. To...
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Genes involved in APP-mediated GLUT1 regulation
https://braincanada.ca/fr/subventions-financées/genes-involved-in-app-mediated-glut1-regulationAlzheimer’s disease is the most common form of dementia. Project Overview Alzheimer’s disease is the most common form of dementia. The brains of many of the patients are less well supplied with glucose (sugar), but not much research aims to understand why this happens. Further, a protein of central...
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Genetic and therapeutic dependencies in SHH driven childhood medulloblastoma
https://braincanada.ca/fr/subventions-financées/genetic-and-therapeutic-dependencies-in-shh-driven-childhood-medulloblastomaMedulloblastoma is the most common malignant brain tumour of childhood, affecting 60-80 Canadian children per year. Project Overview Medulloblastoma is the most common malignant brain tumour of childhood, affecting 60-80 Canadian children per year. The treatment for medulloblastoma comprises...
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Genome-wide discovery and clinical translation of tandem repeat expansions in brain disorders
https://braincanada.ca/fr/subventions-financées/genome-wide-discovery-and-clinical-translation-of-tandem-repeat-expansions-in-brain-disordersBrain disorders are among the leading causes of death and disability worldwide, affecting about 3.6 million Canadians. While we know that genetics play an important role, the specific genetic causes remain unknown for most people with the disorders. Project Overview Brain disorders are among the...
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Genomic markers of cerebral small vessel ischemia
https://braincanada.ca/fr/subventions-financées/genomic-markers-of-cerebral-small-vessel-ischemiaThe overall goal of this research program is to identify genomic markers that predict small vessel disease of the brain. Project Overview The overall goal of this research program is to identify genomic markers that predict small vessel disease of the brain. Specifically we will investigate...