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Maria Vera Ugalde adore la biologie fondamentale. Biochimiste à l'université McGill, elle passe ses journées à utiliser des techniques de microscopie avancées pour observer le fonctionnement complexe de nos cellules. Cette nouvelle façon d'observer certaines protéines protectrices permettra-t-elle...

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating neurodegenerative diseases which have overlap in pathological features and the genetic basis. Project Overview Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two devastating...

Medulloblastoma (MB) is a brain cancer that affects children. Medulloblastoma (MB) is a brain cancer that affects children. Current treatment for MB leaves patients with debilitating brain issues. We found that aggressive MB have low activity of a process called nonsense mediated decay (NMD)....

Women have a higher lifetime risk of Alzheimer’s disease (AD), possibly due to female-specific factors like menopause and pregnancy history. Project Overview Women have a higher lifetime risk of Alzheimer’s disease (AD), possibly due to female-specific factors like menopause and pregnancy history....

TDP-43 is an essential DNA/RNA binding protein at the epicenter of Amyotrophic Lateral Sclerosis (ALS). Project Overview TDP-43 is an essential DNA/RNA binding protein at the epicenter of Amyotrophic Lateral Sclerosis (ALS). Nearly all cases of ALS present with TDP-43 pathology involving nuclear to...

We are working on an innovative project to improve speech therapy for children who have trouble speaking or understanding language. Project Overview We are working on an innovative project to improve speech therapy for children who have trouble speaking or understanding language. We’re using a type...

Depression is a common mental health condition that affects millions of Canadians. Project Overview Depression is a common mental health condition that affects millions of Canadians. While there are treatment options available, some patients do not respond to conventional antidepressants and...

Parkinson’s disease is a neurodegenerative movement disorder. Project Overview Parkinson’s disease is a neurodegenerative movement disorder. At the cellular level, one of the main features of Parkinson’s disease is the clumping of a protein called alpha-synuclein. The disease gets worse as this...

CanChild’s ‘F-words for Child Development’ offer a fresh way for everyone to look at health. Based on WHO concepts, they present a holistic, strengths-based, function-promoting, family-centred approach to child health. Project Overview CanChild’s ‘F-words for Child Development’ offer a fresh way...