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One percent of Alzheimer’s disease is the early-onset type that runs in families. Project Overview One percent of Alzheimer’s disease is the early-onset type that runs in families. Extensive studies of these ultra-rare forms of Alzheimer’s disease have revealed the genes that cause them. On the...

Roughly 10-20% of people self-report use of cannabis during pregnancy. Project Overview Canadian Consortium for the Investigation of Cannabinoids (CCIC) Neuroscience Fellowship in Cannabis and Cannabinoid Research Roughly 10-20% of people self-report use of cannabis during pregnancy. Human studies...

The highest lifetime risk of stroke is the week surrounding birth, with perinatal arterial ischemic stroke (AIS) the most common stroke subtype during this period. The highest lifetime risk of stroke is the week surrounding birth, with perinatal arterial ischemic stroke (AIS) the most common stroke...

There are many neurological and neuropsychiatric diseases that affect men and women differently, and the reasons for this are not well understood. Project Overview There are many neurological and neuropsychiatric diseases that affect men and women differently, and the reasons for this are not well...

Subcellular compartmentalization between the nucleus and cytoplasm is primarily governed by two systems; 1) active nucleocytoplasmic transport (NCT) regulated by Ran-GTPase and involving nuclear transport receptors such as Importin β-1, and 2) macromolecular nuclear pore complexes (NPCs) Project...

Huntington disease (HD) is an inherited disorder that causes brain cells to die and impacts approximately 1 in 7000 Canadians. Project Overview Huntington disease (HD) is an inherited disorder that causes brain cells to die and impacts approximately 1 in 7000 Canadians. A person with HD experiences...

One of the largest predictors of mental illness is childhood emotional and behavioural problems (EBP, e.g., aggression, anxiety, depression), which occur in 12-26% of children under age 6 years. Project Overview One of the largest predictors of mental illness is childhood emotional and behavioural...

En 2016, Yasser Iturria-Medina, Ph.D., et son superviseur postdoctoral de l’époque, Alan Evans, Ph.D., ont publié des résultats qui ont tranquillement contribué à modifier la façon dont les scientifiques envisagent la maladie d’Alzheimer. Aujourd’hui, ces travaux ont donné lieu à plusieurs brevets...

Complex research questions in neurology are often most effectively addressed by monitoring brain structure and function in human patients and live animals in experimental disease models. Project Overview Complex research questions in neurology are often most effectively addressed by monitoring...

Medulloblastoma isthe most common brain cancer in children. Project Overview Medulloblastoma isthe most common brain cancer in children. The current treatment for it includestoxic chemotherapy drugs which leadsto severe long-term side effectslike cognitive impairment. Still, the treatment failsfor...