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Ensuring equitable access to inpatient rehabilitation for people living with dementia: An effectiveness-implementation randomized trial
https://braincanada.ca/fr/subventions-financées/ensuring-equitable-access-to-inpatient-rehabilitation-for-people-living-with-dementia-an-effectiveness-implementation-randomized-trialOne in five older adults with dementia is hospitalized each year. Project Overview One in five older adults with dementia is hospitalized each year. One in three hospitalized older adults will lose independence in transferring, eating, ambulating, dressing, or bathing, which increases nursing home...
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Entretien avec Nicole McKenzie
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/entretien-avec-nicole-mckenziekk Nous avons interrogé Nicole McKenzie, gestionnaire de projet et facilitatrice de la recherche sur les lésions de la moelle épinière au Foothills Medical Centre de Calgary, en Alberta, sur l'impact et les réalisations d'un projet qui a bénéficié du soutien d'une subvention de plateforme de Brain...
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Epigenetic mechanisms underlying dendritic atrophy in ALS
https://braincanada.ca/fr/subventions-financées/epigenetic-mechanisms-underlying-dendritic-atrophy-in-alsMotor neurons are made up of three distinct regions. The top of the neuron is composed of branches like a tree called dendrites that receive information to transmit. Project Overview Motor neurons are made up of three distinct regions. The top of the neuron is composed of branches like a tree...
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Epigenetics and mental health: the Canadian neuroepigenetics network
https://braincanada.ca/fr/subventions-financées/epigenetics-and-mental-health-the-canadian-neuroepigenetics-networkPsychiatry, like all areas of medicine and biology, has long considered the origins of individual differences. Project Overview Psychiatry, like all areas of medicine and biology, has long considered the origins of individual differences. This issue ultimately produced a nature vs nurture schism...
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Epitranscriptomic regulation of sleep, neurodegeneration, and longevity
https://braincanada.ca/fr/subventions-financées/epitranscriptomic-regulation-of-sleep-neurodegeneration-and-longevityThis research proposal investigates how a chemical modification called N6-methyladenosine (m6A) on messenger RNA influences brain health, specifically focusing on its role in sleep regulation, learning and memory, and neurodegenerative diseases such as Alzheimer’s. This research proposal...
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Est-il possible de cibler la cause première de la SLA liée au gène C9ORF72 ?
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/est-il-possible-de-cibler-la-cause-profonde-de-l-als-liée-au-gène-c9orf72Dr Christopher E. Pearson (à gauche) et Dr Ekaterina Rogaeva Le contrôle de l'expansion d'une répétition d'ADN peut indiquer la voie à suivre pour un traitement futur "La meilleure chose à faire en tant que scientifique dans ce domaine, ce sont les personnes avec lesquelles nous travaillons et les...
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Establishing protein signatures of MRI-detected vascular brain injury in circulating endothelial-derived extracellularvesicles in Alzheimer’s disease
https://braincanada.ca/fr/subventions-financées/establishing-protein-signatures-of-mri-detected-vascular-brain-injury-in-circulating-endothelial-derived-extracellularvesicles-in-alzheimer-s-diseaseAge-related dementias are reaching epidemic levels, affecting over 600,000 Canadians. Project Overview Age-related dementias are reaching epidemic levels, affecting over 600,000 Canadians. The most common cause of age-related dementia is Alzheimer’s disease (AD). The defining pathology of AD is the...
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EthoLab: A platform for neurophysiological studies of natural behavior
https://braincanada.ca/fr/subventions-financées/etholab-a-platform-for-neurophysiological-studies-of-natural-behaviorSystems neuroscience owes much of its success to an empirical tradition of using simplified laboratory settings that carefully control sensory stimuli, motor responses, or other task-relevant variables in order to identify the neural mechanisms underlying different behavioral functions. Project...
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Evaluating an innovative e-mental health solution to support youth with mental health disorders in Northwestern Ontario
https://braincanada.ca/fr/subventions-financées/evaluating-an-innovative-e-mental-health-solution-to-support-youth-with-mental-health-disorders-in-northwestern-ontarioMany youth suffer from mental health-related brain disorders which can have devastating consequences Effective treatment is desperately needed. Project Overview Many youth suffer from mental health-related brain disorders which can have devastating consequences Effective treatment is desperately...
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Evaluating DLK activity in brain samples from Huntington’s disease patients
https://braincanada.ca/fr/subventions-financées/evaluating-dlk-activity-in-brain-samples-from-huntington-s-disease-patients"Background:Within the realm of neurodegenerative diseases, there is still a lack of effective disease-modifying treatments. Huntington’s Disease (HD) is no less immune to this issue, with only symptomatic treatment options being available for patients." Project Overview “Background:Within the...