Subventions financées

Neuroinflammation has been implicated in a diverse array of degenerative conditions, ranging from Multiple Sclerosis  to  Alzheimer’s  disease.

Optogenetic strategies – the ability to activate normally light-insensitive neurons with light – are being used in clinical trials to restore light sensitivity to the retina of vision impaired patients.

Multiple Sclerosis (MS) is a disease where the immune system attacks the brain and spinal cord.

Dr Bambico proposes to test a new and potentially groundbreaking experimental technique called EC stimulation, which will enable researchers to influence the activity of different kinds of neurons in any part of the brain without the need of major brain invasive surgery or complex genetic techniques.

The brain cells in Alzheimer’s disease patients differ extensively from healthy brain cells at the molecular level: there are hundreds of genes that are normally active in the brain, but become inactive in Alzheimer’s.

Epilepsy is a debilitating neurological disorder that affects up to one percent of the world’s population. A third of epileptic patients suffer from drug-resistant form of the disease for which brain surgical intervention is often necessary.

Neuropathic pain is a chronic pain disorder resulting from damage to the nerves.

My time in the Courtine laboratory provided an opportunity to obtain hands-on experience in the application of scRNA-seq to understand the pathobiology of SCI, through two different projects.