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799 résultats trouvés

New function for DEPTOR tyrosine 289 phosphorylation in glioma metabolism

Deregulation of brain cell metabolism is commonly observed in low-grade brain cancers.


Domaine de recherche
Le cancer
Concours
Subventions de fonctionnement du CRS
Province
Québec
DATE DE DÉBUT
2025

Targeting a keystone bacterial periodontal pathogen to mitigate neurodegenerative changes in Alzheimer’s disease

Periodontal disease has links with Alzheimer’s disease.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Neurodégénérescence
Province
Québec
DATE DE DÉBUT
2025

Enhancing Support for Alzheimer’s Caregivers: A Comprehensive Approach to Caregiver Needs and Healthcare Integration Across the Disease Trajectory

In Canada, about 1.1 million people care for family members with dementia, providing support that saves the healthcare system billions each year.


TYPE DE SUBVENTION
Subventions pour la mobilisation des connaissances
Domaine de recherche
Neurodégénérescence
Province
Ontario
DATE DE DÉBUT
2025

Evaluating the role of intestinal inflammation in Alzheimer’s Disease

Recent findings suggest that the gut and brain are closely connected, and this link may be important in Alzheimer’s disease (AD).


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Neurodégénérescence
Province
Ontario
DATE DE DÉBUT
2025

The Douglas-Bell Canada Brain Bank: supporting human brain research in Canada and beyond

The Douglas-Bell Canada Brain Bank (DBCBB; douglasbrainbank.ca), based at the Douglas Research Centre (McGill University affiliate), has become one of the most important brain banks in the world.


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Neurotechnologie
Province
Québec
DATE DE DÉBUT
2025

No Caregiver Left Behind: Addressing Accessibility and Sustainability of an ACT Intervention for Family Caregivers of People with Neurodevelopmental Disabilities

Caring for a family member with a neurodevelopmental disability (NDD) can be challenging, often leading to high levels of anxiety and depression.


Domaine de recherche
Développement neurologique
Concours
Programmes d'innovation et de mise en œuvre du KBHN
Province
Ontario
DATE DE DÉBUT
2025

TACAN regulates mesenchymal versus amoeboid cell states in glioblastoma

Glioblastoma Multiforme (GBM) is the most common and aggressive brain tumour in adults.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Le cancer
Concours
Prix Rising Stars pour les stagiaires
Province
Ontario
DATE DE DÉBUT
2025

Development of a diagnostic amyloid-β seed amplification assay to discriminate between Alzheimer’s disease with and without cerebral amyloid angiopathy

In Alzheimer’s disease (AD), the pathogenic amyloid-beta protein accumulates in the brain parenchyma and vessel walls.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Neurodégénérescence
Province
Ontario
DATE DE DÉBUT
2025

The Canadian Optogenetics and Vectorology Foundry

Optogenetics, defined as a technique where light-sensitive genes are introduced into brain cells to control their activity with light, allows researchers to precisely control nerve cell communication thereby, transforming brain research.


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Système nerveux central
Province
Québec
DATE DE DÉBUT
2025

Linking reduced cell-specific inhibition to abnormal brain activity in chronic stress

Depression is a leading cause of disability, with a large proportion of treatment-resistant patients. Recent studies have implicated reduced brain inhibition in human depression from a specific neuron type (SST), and new pharmacology boosting this reduced inhibition led to antidepressant and pro-cognitive effects in rodents.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Santé mentale
Province
Ontario
DATE DE DÉBUT
2025