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799 résultats trouvés

Prototype NIR Ca2+ indicators into refined tools that can be applied for neuronal activity imaging in model organisms

One of the major challenges facing the BRAIN initiative is the development of technologies that will enable the recording of neural activity throughout the entire volume of a rodent brain.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurotechnologie
Province
Alberta
DATE DE DÉBUT
2015

Identification of novel genes causing intracranial aneurysms

Stroke is the leading cause of disability among adults and one of the three leading causes of death in North America.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Blessures
Concours
Subvention de la Fondation des maladies du cœur
Province
Terre-Neuve et Labrador
DATE DE DÉBUT
2015

Mitochondrial calcium uptake and targeted therapeutics

Stroke is the sudden death of brain cells caused by insufficient blood supply to the brain. Parts of the brain that enable us to walk and talk are often damaged most by a stroke.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Blessures
Concours
Subvention de la Fondation des maladies du cœur
Province
Nouvelle-Écosse
DATE DE DÉBUT
2015

Mechanisms of delayed death in stroke

Stroke is a major cause of death and disability. At present, there are no clear and effective therapies to aid the majority of patients who suffer stroke.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Blessures
Concours
Subvention de la Fondation des maladies du cœur
Province
Ontario
DATE DE DÉBUT
2015

Role of ATF4 and P53 family transcription factors in the regulation of neuronal cell death

Stroke is a leading cause of adult long term disability and the third leading cause of death in industrialized countries.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Blessures
Concours
Subvention de la Fondation des maladies du cœur
Province
Ontario
DATE DE DÉBUT
2015

Synaptic mechanisms in post-stroke depression

Stroke affects 17% of people worldwide and some estimates predict that it will soon become the most common cause of death worldwide.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Blessures
Concours
Subvention de la Fondation des maladies du cœur
Province
Ontario
DATE DE DÉBUT
2015

Habitual physical activity, exercise and cardiovascular function in spinal cord injury

The major objectives of this research program are to measure the function of the heart and blood vessels following SCI and to investigate the mechanisms that are responsible for any changes that occur.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Blessures
Concours
Initiative des leaders de recherche émergents de la Fondation des maladies du cœur
Province
Colombie-Britannique
DATE DE DÉBUT
2015

Genomic markers of cerebral small vessel ischemia

The overall goal of this research program is to identify genomic markers that predict small vessel disease of the brain.


TYPE DE SUBVENTION
Subventions pour le renforcement des capacités
Domaine de recherche
Blessures
Concours
Initiative des leaders de recherche émergents de la Fondation des maladies du cœur
Province
Colombie-Britannique
DATE DE DÉBUT
2015

Regulation of the stress granule proteome and transcriptome by TDP-43 in ALS: biomarkers and therapeutic targets

When cells are under stress, one of the reactions is to form tiny clumps called stress granules that protect important genetic information while protective mechanisms kick in.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurodégénérescence
Province
Québec
DATE DE DÉBUT
2015

Discovery of Therapeutic Targets for FUS- and TDP43-Dependent Forms of ALS

The four most commonly studied ALS proteins are SOD1, TDP-43, FUS and C9ORF72


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurodégénérescence
Province
Ontario
DATE DE DÉBUT
2015