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830 résultats trouvés

Drug Delivery across the Human Blood-Brain Barrier

Toxic amyloid proteins are known to be a significant contributing factor in the development of Alzheimer’s disease.


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Neurodégénérescence
Concours
CQDM - Brain Canada - Pleins feux sur le cerveau
Province
Ontario
DATE DE DÉBUT
2015

Cyto-iGluSnFR: A glutamate biosensor platform for brain diseases

The team wants to take a new breakthrough technology called Cyto-iGluSnFR (pronounced “sight-oh-eye-glue-sniffer”) and adapt it for the discovery of drugs to treat a variety of brain and eye diseases.


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Neurotechnologie
Concours
CQDM - Brain Canada - Pleins feux sur le cerveau
Province
Québec
DATE DE DÉBUT
2015

‘Best in Class’ Platform for Blood Brain Barrier Delivery of Therapeutics

The blood-brain barrier (BBB) plays an essential role in protecting the brain from blood-borne diseases.


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Multiple
Concours
CQDM - Brain Canada - Pleins feux sur le cerveau
Province
Ontario
DATE DE DÉBUT
2015

Preclinical development of a disease modifying small molecule therapy for Alzheimer disease

No medications exist that can stop or even slow the progression for Alzheimer Disease (AD).


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Neurodégénérescence
Province
Colombie-Britannique
DATE DE DÉBUT
2015

Modulating memory circuits: focal DBS treatments to improve medial temporal lobe function

Two diseases that show very different trajectories have nevertheless led researchers to identify dysfunction in a common brain network.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Multiple
Province
Ontario
DATE DE DÉBUT
2015

Biomarkers for Crossing the Translational Divide in Acute Spinal Cord Injury

Each year, over 1,500 Canadians sustain an acute spinal cord injury (SCI), and join close to 40,000 across our nation living with one of the most physically and psychologically devastating of injuries.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Blessures
Province
Colombie-Britannique
DATE DE DÉBUT
2015

Adolescent Mental Health

Most mental disorders begin in adolescence; however, there are many gaps in our understanding of youth mental health.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Santé mentale
Province
Alberta
DATE DE DÉBUT
2015

Targeting the Synaptic Pathway in Neurodevelopmental and Psychiatric Disorders

Autism spectrum disorders are neurodevelopmental disorders characterized by deficits in social interaction, poor communication, and restricted, stereotyped patterns of behavior.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Multiple
Province
Colombie-Britannique
DATE DE DÉBUT
2015

Understanding stress to improve mental health

Recent estimates indicate that 1 in 5 Canadians are affected annually by mood, anxiety and other mental illnesses.


TYPE DE SUBVENTION
Subventions d'équipe
Domaine de recherche
Santé mentale
Province
Alberta
DATE DE DÉBUT
2015

Human MiniPromoters for Restricted Expression of Ocular Gene Therapy

The purpose of this project is to develop promoters. Promoters are pieces of DNA, which act as switches to turn genes on and off.


TYPE DE SUBVENTION
Subventions de la plate-forme
Domaine de recherche
Système sensoriel
Concours
CQDM - Brain Canada - Pleins feux sur le cerveau
Province
Colombie-Britannique
DATE DE DÉBUT
2015