737 results found
Building the Rick Hansen Alberta Spinal Cord Injury Registry
Project Overview
There are an estimated 86,000 people living with a spinal cord injury (SCI) in Canada, with an annual economic burden of $2.67 billion for those surviving the initial injury. Approximately half of SCIs are the result of a traumatic (T) incident (ex. motor vehicle accident, sports injury) and the other…
Project Complete
See the project and researchersA national coordinating neuroinformatics framework for autism and related conditions
Project Overview
New approaches in neurodevelopmental research increasingly seek to integrate enormous amounts of data through sophisticated informatics so as to determine the relationship between genotype and phenotypes, both structural and functional, as they change over time during development. Such approaches dwarf the resources of most laboratories, who are increasingly moving toward…
Project Complete
See the project and researchersNovel approaches to early detection and treatment of ASD
Project Overview
More than 1 in 100 individuals are diagnosed with Autism Spectrum Disorder (ASD), with profound impacts on the quality of life of those who are affected and their families. Until recently, children were rarely referred for assessment before age 2, so we knew little about ASD early in life. Prior…
Project Complete
See the project and researchersTesting therapeutic approaches to improve cognitive dysfunction in a primate model of Alzheimer’s Disease
Project Overview
Alzheimer’s Disease (AD) is a severe dementia that is likely a result of years of buildup in the brain of molecules called amyloid-beta oligomers (AβOs). The pursuit of new disease-modifying therapeutics for AD that change the natural progression of AD early in its course is under intense investigation. A major…
Project Ongoing
See the project and researchersNovel approaches to understand the role of cAMP and co-signaling cascades in synaptic plasticity and brain disorders
Project Overview
Synaptic plasticity is the process where the strength of connections between nerve cells is altered by experience. It is widely believed that synaptic plasticity is used to store information in the brain and is important for learning and memory and other major cognitive processes. The most widely studied form of…