Directory of funded grants

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799 results found

Sleep, cognition, and inflammation following natural or surgical menopause

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer’s Association Research Fellowship

  • Province

    Ontario

  • Start Date

    2017

  • Total Grant Amount

    $181,295

  • Health Canada Contribution

    $90,648

Project Overview

Alzheimer’s disease disproportionately affects women and emerging evidence suggests there may be unique biological and lifestyle factors that underlie these differences. A woman’s brain health, for example, may be affected more strongly than a man’s by the presence of APOE-e4, a gene variant linked to Alzheimer’s risk. Nicole Gervais, Ph.D.,…

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Preventing Language Decline in Dementia 

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer’s Association International Grant Program

  • Province

    Ontario

  • Start Date

    2016

  • Total Grant Amount

    $109,068

  • Health Canada Contribution

    $54,534

Project Overview

Primary progressive aphasia (PPA) is a form of dementia which impairs the ability to understand spoken and written language but other cognitive skills (including memory) remain intact for several years after its onset. Ideally, interventions to improve communication abilities in people with PPA would begin during the earliest stages when…

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The Automated Monitoring of Gait as a Predictor of Fall Risk

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer’s Association International Grant Program

  • Province

    Ontario

  • Start Date

    2016

  • Total Grant Amount

    $131,578

  • Health Canada Contribution

    $65,789

Project Overview

People with dementia are at a high risk for falls which are a leading cause of injury and can contribute to loss of independence and quality of life. Many falls could be prevented if there was a way to predict an individual’s likelihood of falling and offer interventions to reduce…

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Toxicity Pathways and Catalytic Potential of Cu-Containing AB Oligomers

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Alzheimer’s

  • Competition

    Alzheimer’s Association International Grant Program

  • Province

    British Columbia

  • Start Date

    2016

  • Total Grant Amount

    $136,468

  • Health Canada Contribution

    $68,234

Project Overview

The protein fragment beta-amyloid has long been a key suspect in Alzheimer’s disease. Beta-amyloid molecules have a normal function, but in Alzheimer’s they form clumps called oligomers and plaques that may be toxic to nerve cells. Recent studies indicate that beta-amyloid is more likely to form toxic clumps when it…

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Pathogenic Mechanism of C9orf72 haploinsufficiency in ALS/FTLD: a road to therapeutic discovery

  • Grant Type

    Team grants

  • Area of research

    Neurodegeneration

  • Disease Area

    ALS

  • Competition

    ALS Arthur J. Hudson Translational Team Grant

  • Province

    Ontario

  • Start Date

    2017

  • Total Grant Amount

    $1,647,800

  • Health Canada Contribution

    $823,900

Project Overview

In this Hudson project, the team led by Dr. Robertson will pursue a comprehensive understanding of the normal functions of C9ORF72 and provide a better determination of whether loss of these functions via mutation may cause or contribute to ALS. One of the first discoveries about C9ORF72 was that it…

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