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Longitudinal single-cell multiomic profiling toward elucidating the differential roles of sex and hormones on the molecular programming of the brain

  • Grant Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2023

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

There are many neurological and neuropsychiatric diseases that affect men and women differently, and the reasons for this are not well understood. One factor that may be important is the influence of hormones during puberty, which can cause changes in gene expression that affect how the brain works. Our goal…

Project Ongoing

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The 5kEEG project: Large-scale Electrophysiological Investigation of Autism and Neurodevelopmental Disorders

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodevelopment

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2023

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The 5kEEG project is a pioneering study that aims to improve our understanding of autism and neurodevelopmental disorders by investigating brain activity. The diagnosis and treatment of these complex conditions are challenging due to limited knowledge of their root causes. The 5kEEG project will examine the brain activity of 5,000…

Project Ongoing

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Developing a new model to study microglia and macrophage function in slowly expanding lesions of multiple sclerosis

  • Grant Type

    Capacity building grants

  • Area of research

    Neurodegeneration

  • Disease Area

    Multiple Sclerosis

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Saskatchewan

  • Start Date

    2023

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Multiple sclerosis (MS) is a neurodegenerative disease in the brain and spinal cord of the central nervous system (CNS). Canada has amongst the highest rate of MS in the world and Canadians living with MS have lifelong disease that progressively worsens and reduces their quality of life. Although there are…

Project Ongoing

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Atypical neuronal communication mechanisms disrupted in neurodevelopmental disease

  • Grant Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Other

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Manitoba

  • Start Date

    2023

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

The diversity of neurodevelopmental and neuropsychiatric disease can be commonly unified by fundamental deficits in neuronal communication, particularly at the interface between neurons known as the synapse. Nevertheless, the molecular components facilitating these critical neuronal communication networks remain to be fully elucidated. Previously, we understood that neuronal communication mechanisms heavily…

Project Ongoing

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Mechanistic Studies of Metabolite-Signaling Defects Causing Seizures

  • Grant Type

    Capacity building grants

  • Area of research

    Central Nervous System

  • Disease Area

    Autism

  • Competition

    Future Leaders in Canadian Brain Research

  • Province

    Québec

  • Start Date

    2023

  • Total Grant Amount

    $100,000

  • Health Canada Contribution

    $50,000

Project Overview

Our research program is centered on investigating the important contributions of metabolism to brain health. It is generally well-accepted that proper nutrition is a major “environmental factor” that is essential for good health, yet the underlying molecular mechanisms that contribute to health are poorly understood, particularly within the central nervous…

Project Ongoing

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