770 results found
Intensive Cancer Screening for Cryptogenic Stroke (INCOGNITO) Pilot Randomized Trial
Project Overview
The first question people ask after suffering a stroke is: "Why?" A straightforward question, but for 4 in 10 stroke survivors, it's also unanswerable. These are the people for whom routine tests reveal no identifiable cause for the blood clot that may lead to their disability and premature death. And…
Project Ongoing
See the project and researchersblooD prEssure management in sTroke following EndovasCular Treatment (DETECT)
Project Overview
Most strokes occur from clots blocking vessels that supply blood flow to the brain. A large blockage in one of the main brain vessels is identified in up to 1/3 of patients presenting with stroke. Endovascular thrombectomy is a procedure that is effective at removing clots and restoring blood flow…
Project Ongoing
See the project and researchersDevelopment and testing of a system for remote ischemic conditioning in preparation for clinical trials in cerebral small vessel disease and pre-hospital stroke care
Project Overview
One in four strokes are caused by a condition called cerebral small vessel disease (CSVD). There are no approved treatments for CSVD. There also no treatments for patients with stroke who are being transported to hospital in typical ambulances. A promising therapy for both these settings is “remote ischemic conditioning”…
Project Ongoing
See the project and researchersA multi-centre, prospective, randomized, open-label, blinded endpoint (PROBE) controlled trial comparing acute cervical internal carotid artery stenting to no stenting during endovascular thrombectomy for anterior circulation stroke due to acute tandem occlusion: Endovascular Acute Stroke Intervention – Tandem OCclusion trial (EASI-TOC)
Project Overview
Ischemic stroke occurs when a person suffers a sudden blockage of an artery in their brain. Severe strokes caused by blockage of large brain arteries are treated with a very effective mechanical clot-removal procedure called thrombectomy. However, there are still unanswered questions regarding certain subgroups of thrombectomy-treated stroke patients. One…
Project Ongoing
See the project and researchersAdaptive Platform Trial to Investigate VArious ThErapies in Carotid-Associated Stroke (ACTIVATE-CAS)- Pilot Phase
Project Overview
Carotid disease accounts for 10% of ischemic strokes and has high rate of recurrence of up to 30%-50%(1, 2). There is lack of adequate updated data on its prevalence, recurrence rates and treatment options. This is especially true for newly identified disease mechanisms like carotid web and low grade stenosis(3,…