721 results found
Parent-therapist partnership to provide early, intensive exercise to enhance walking outcomes in children with perinatal stroke
Project Overview
Perinatal (around birth) stroke is devastating, because the effects are life-long. Current treatments to improve walking are limited, and largely passive, such as stretching, bracing, botulinum toxin injections and surgery. Recent work in animals indicates that intensive active therapy is effective in the young, when nerve pathways for movement are…
Project Ongoing
See the project and researchersImplementation of a Clinical Pathway for Acute Care of Pediatric Concussion: Uptake, Outcomes, and Health Care Impacts
Project Overview
Each year, 1-2 million children in North America suffer a concussion. Guidelines exist to manage the care of concussion in children but have not been implemented consistently. As a result, clinical practice varies widely from one health provider to another. This may be because clinical guidelines have not been translated…
Project Complete
See the project and researchersImproving Quality of Life in the Elderly by Standardizing Care for Neuropsychiatric Symptoms of Dementia
Project Overview
Aggression and agitation are common symptoms among patients with dementia. These symptoms are the leading cause for hospitalization and admission to long-term care homes. Medication treatments that are commonly used to treat these symptoms have significant adverse effects including falls, stroke and increased risk of death. These adverse effects are…
Project Ongoing
See the project and researchersInvestigating the Neurodevelopmental Trajectory of Emotional Face Processing in Autism Spectrum Disorder
Project Overview
An understanding of emotional information from faces is critical for successful social interactions. A key component of ASD is poor social functioning. Deficits and dysfunction in the ‘social network’ of the brain have been reported in ASD, as well as differences in how individual regions of the brain communicate with…
Project Complete
See the project and researchersInterleukin-1 blockade along with hypothermia to prevent cerebral palsy arising from refractory neonatal asphyxia
Project Overview
Neonatal asphyxia and subsequent cerebral palsy (CP) is a severe pathology resulting from lack of oxygen and/or infection-inflammation. This disease still leads to mortality or severe brain injuries and long-term disabilities. Therapeutic hypothermia (decreased body temperature to 33-34°C during 3 days) is the only treatment available for these newborns. Despite…