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Huntington disease (HD) is caused by a CAG trinucleotide repeat expansion within the huntingtin (HTT) gene which produces a mutant HTT (mHTT) protein. This mHTT protein aggregates within neurons, forming fibrils that interfere with cellular functions and result in neurodegeneration. The...

The brain requires a large amount of energy and oxygen for survival. Project Overview The brain requires a large amount of energy and oxygen for survival. In order to meet these requirements, the blood supply to the brain is tightly controlled to ensure that active areas receive more blood....

Contrary to popular belief, spinal cord injuries are rarely complete. Project Overview Contrary to popular belief, spinal cord injuries are rarely complete. The brain retains access to the spinal cord circuitry below the lesion, but this connection is often dormant. Recently, stimulation of brain...

Parent-child brain-to-brain synchrony is the coordinated interplay of brain activity between parent and child, which is believed to be evolutionarily important for strengthening bond formation Project Overview Parent-child brain-to-brain synchrony is the coordinated interplay of brain activity...

The proposed initiative will make every brain tumour count! Project Overview The proposed initiative will make every brain tumour count! We will enhance the Canadian Cancer Registry (CCR) and brain tumour research capacity by providing data on an additional 40% of primary brain tumours diagnosed...

People living in long-term care (LTC) homes are often socially isolated. Project Overview People living in long-term care (LTC) homes are often socially isolated. Evidence shows virtual reality (VR) can be used to support the mental health of older adults. Virtual programming supports access to...

Recording the electrical impulses of neurons with optical methods in the brain will be enormously beneficial for understanding how the healthy brain functions, as well as how diseases of the brain impact its normal function. Project Overview Recording the electrical impulses of neurons with optical...

L'université Brock est à l'avant-garde d'un mouvement qui bénéficie d'un important coup de pouce pour rendre les neurosciences plus ouvertes et accessibles dans le monde entier. Lire l'article complet ici.

Alzheimer's disease causes memory loss due to progressive brain damage. Current treatments only offer modest symptomatic relief, highlighting the need for new approaches. Project Overview Alzheimer's disease causes memory loss due to progressive brain damage. Current treatments only offer modest...

Neuroscience is on the brink of a digital revolution, where vast amounts of data from diverse individuals are supporting the creation of powerful predictive models of brain disorders. Project Overview Neuroscience is on the brink of a digital revolution, where vast amounts of data from diverse...