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The team wants to take a new breakthrough technology called Cyto-iGluSnFR (pronounced “sight-oh-eye-glue-sniffer”) and adapt it for the discovery of drugs to treat a variety of brain and eye diseases. Project Overview The team wants to take a new breakthrough technology called Cyto-iGluSnFR...

Recently, Dr. Honglin Luo, in collaboration with Dr. Neil Cashman, discovered that mutations in the ALS-linked SOD1 gene result in activation of a specific neuroinflammatory pathway called cGAS-STING. Project Overview Recently, Dr. Honglin Luo, in collaboration with Dr. Neil Cashman, discovered...

#BreakTheBias est le thème de la Journée internationale de la femme 2022, à l'occasion de laquelle les défenseurs des droits de l'homme de tout le Canada se joignent à l'appel pour imaginer un monde diversifié, équitable et inclusif. Pour Brain Canada et Women's Brain Health Initiative (WBHI), il...

Gamma oscillations (GO) are electrical signals detected in the brain that are essential for memory and cognition. Project Overview Gamma oscillations (GO) are electrical signals detected in the brain that are essential for memory and cognition. GO are a product of the activity of a subpopulation of...

In childhood, medulloblastoma (a form of brain cancer) and neuroblastoma (a cancer that starts in the nerve cells) can be aggressive and hard to treat. Project Overview In childhood, medulloblastoma (a form of brain cancer) and neuroblastoma (a cancer that starts in the nerve cells) can be...

Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in humans. Project Overview Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in humans. The disease is caused by the degeneration of motor neurons that innervate the voluntary...

ALS is a disease that is characterized by degeneration of both upper and lower motor neurons, and while a significant proportion of work has focused on motor neurons in the spinal cord, the motor cortex in the brain, where electrical signals to your muscles originate have clear, but poorly Project...

The brain cells in Alzheimer’s disease patients differ extensively from healthy brain cells at the molecular level: there are hundreds of genes that are normally active in the brain, but become inactive in Alzheimer’s. Project Overview The brain cells in Alzheimer’s disease patients differ...

Infants born early (preterm) are at risk for brain injury and long term neurodevelopmental challenges, including delays in walking, language development, and school-aged cognitive performance. Project Overview Infants born early (preterm) are at risk for brain injury and long term...

Epilepsy is a debilitating disease affecting 1% of the world’s population. Project Overview Epilepsy is a debilitating disease affecting 1% of the world’s population. It is characterized by an enduring propensity to recurring seizures. One of the cornerstones of the diagnosis and management of...