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Brain channelopathies: target validation and novel therapeutic strategies
https://braincanada.ca/fr/subventions-financées/brain-channelopathies-target-validation-and-novel-therapeutic-strategiesThe entry of calcium ions into cells is mediated by a class of protein (called calcium channels) that responds to electrical signals by opening of a calcium-selective pore. Project Overview The entry of calcium ions into cells is mediated by a class of protein (called calcium channels) that...
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Brain-Computer Interface Integrated Augmentative and Alternative Communication
https://braincanada.ca/fr/subventions-financées/brain-computer-interface-integrated-augmentative-and-alternative-communicationThe primary objective of Ms. Shea’s research is to investigate an optimized integration of event related potentials (ERPs) as a means to augment assistive communication devices. Project Overview The primary objective of Ms. Shea’s research is to investigate an optimized integration of event related...
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Brain development in moderate to late preterm infants – exploring the relationship between perinatal inflammatory marker profiles and brain development disruptions
https://braincanada.ca/fr/subventions-financées/brain-development-in-moderate-to-late-preterm-infants-exploring-the-relationship-between-perinatal-inflammatory-marker-profiles-and-brain-development-disruptionsEach year, 12.6 million babies worldwide are born when the pregnancy is between 32-36 weeks. Project Overview Each year, 12.6 million babies worldwide are born when the pregnancy is between 32-36 weeks. This is too early and called moderate-late preterm (MLPT). MLPT babies are more likely to have...
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Brain Gain: Identifying candidate dementia-related biomarkers and early intervention strategies for adults aged 50+ with a history of mild traumatic brain injury
https://braincanada.ca/fr/subventions-financées/brain-gain-identifying-candidate-dementia-related-biomarkers-and-early-intervention-strategies-for-adults-aged-50-with-a-history-of-mild-traumatic-brain-injuryOne hundred and forty-four thousand Canadians suffer a diagnosed concussion each year. Project Overview One hundred and forty-four thousand Canadians suffer a diagnosed concussion each year. A concussion is a type of mild traumatic brain injury, often caused by a bump to the head or body that...
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Brain Health Resources and Integrated Diversity (BRAID) Hub
https://braincanada.ca/fr/subventions-financées/brain-health-resources-and-integrated-diversity-braid-hubThe BRAID Hub (Brain health Resources And Integrated Diversity Hub) addresses critical gaps in Canada’s dementia care system. Project Overview The BRAID Hub (Brain health Resources And Integrated Diversity Hub) addresses critical gaps in Canada’s dementia care system. Focused on building a skilled...
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Brain-heart dynamics in treatment-resistant depression and the effects of repetitive transcranial magnetic stimulation
https://braincanada.ca/fr/subventions-financées/brain-heart-dynamics-in-treatment-resistant-depression-and-the-effects-of-repetitive-transcranial-magnetic-stimulationRepetitive transcranial magnetic stimulation (rTMS) is a non-invasive neurostimulation therapy, recommended by Canadian guidelines as a first-line intervention for major depression that does not respond to an adequate course of pharmacological therapy, known as treatment-resistant depression (TRD)....
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Brain-Heart Research Integrative Innovation Team Endeavor (BHRIITE) – A Paradigm Shift in Brain-Heart Concept and Care
https://braincanada.ca/fr/subventions-financées/brain-heart-research-integrative-innovation-team-endeavor-bhriite-a-paradigm-shift-in-brain-heart-concept-and-careBrain-Heart conditions such as cognitive impairment (trouble remembering and learning) or heart failure (heart muscle unable to pump enough blood) are becoming more common as we age. Project Overview Brain-Heart conditions such as cognitive impairment (trouble remembering and learning) or heart...
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Brain, Mind and Consciousness
https://braincanada.ca/fr/subventions-financées/brain-mind-and-consciousnessThe Azrieli Program in Brain, Mind & Consciousness brings together 22 researchers to examine what consciousness is and how it comes about. Project Overview The Azrieli Program in Brain, Mind & Consciousness brings together 22 researchers to examine what consciousness is and how it comes about. The...
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Brain network-based determination of genes that clear mutant huntingtin fibrils
https://braincanada.ca/fr/subventions-financées/brain-network-based-determination-of-genes-that-clear-mutant-huntingtin-fibrilsHuntington disease (HD) is caused by a CAG trinucleotide repeat expansion within the huntingtin (HTT) gene which produces a mutant HTT (mHTT) protein. This mHTT protein aggregates within neurons, forming fibrils that interfere with cellular functions and result in neurodegeneration. The...
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Brain pericyte calcium signaling during vasomotion and neurovascular coupling
https://braincanada.ca/fr/subventions-financées/brain-pericyte-calcium-signaling-during-vasomotion-and-neurovascular-couplingThe brain requires a large amount of energy and oxygen for survival. Project Overview The brain requires a large amount of energy and oxygen for survival. In order to meet these requirements, the blood supply to the brain is tightly controlled to ensure that active areas receive more blood....