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The proposed research in this application will significantly broaden our understanding of the molecular basis for how stress leads to anxiety and depression. Project Overview The proposed research in this application will significantly broaden our understanding of the molecular basis for how stress...

Ms. Zeinab Mohanna’s research will test the hypothesis that CRISPR/Cas9-mediated genome editing can increase the expression of PAX6 protein, improve the function of the neural and other tissues of the eye, and ultimately rescue the mutant phenotype in the mouse model of aniridia. Project...

Increased metabolism (hypermetabolism) is a characteristic often associated with more aggressive, faster progressing cases of ALS. Project Overview Increased metabolism (hypermetabolism) is a characteristic often associated with more aggressive, faster progressing cases of ALS. Recently, after...

Des éclairs verts et jaunes marquent les endroits où le virus Farmington tue les cellules cibles sensibles (en rouge). David Stojdl et son équipe tentent de traiter différemment les tumeurs cérébrales. Leur laboratoire a mis au point une biothérapie par virus oncolytique spécialement conçue pour le...

Joëlle Pineau, Senior Fellow du programme Learning in Machines and Brains, fait une présentation lors de la réunion de décembre 2015 du programme du CIFAR Learning in Machines and Brains (apprentissage dans les machines et les cerveaux) L'apprentissage dans les machines et les cerveaux est l'un des...

Most nerves in the brain are surrounded by myelin, an insulating cover that allows them communicate efficiently. Project Overview Most nerves in the brain are surrounded by myelin, an insulating cover that allows them communicate efficiently. Brain damage in multiple sclerosis (MS) results from...

Most nerves in the brain are surrounded by myelin, an insulating cover that allows them communicate efficiently. Project Overview Most nerves in the brain are surrounded by myelin, an insulating cover that allows them communicate efficiently. Brain damage in multiple sclerosis (MS) results from...

Un programme intergénérationnel innovant qui réunit dans la cuisine des jeunes et des personnes atteintes de démence. Cuisiner ensemble jumelle de jeunes adultes à des personnes âgées souffrant de perte de mémoire ou de démence et les invite à prendre part à des séances de cuisine pratique pendant...

The team wants to take a new breakthrough technology called Cyto-iGluSnFR (pronounced “sight-oh-eye-glue-sniffer”) and adapt it for the discovery of drugs to treat a variety of brain and eye diseases. Project Overview The team wants to take a new breakthrough technology called Cyto-iGluSnFR...

Recently, Dr. Honglin Luo, in collaboration with Dr. Neil Cashman, discovered that mutations in the ALS-linked SOD1 gene result in activation of a specific neuroinflammatory pathway called cGAS-STING. Project Overview Recently, Dr. Honglin Luo, in collaboration with Dr. Neil Cashman, discovered...