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DBS-PPN-AD: A Pilot Clinical Trial Investigating Deep Brain Stimulation of the Pedunculopontine Nucleus for theTreatment of Alzheimer’s Disease
https://braincanada.ca/fr/subventions-financées/dbs-ppn-ad-a-pilot-clinical-trial-investigating-deep-brain-stimulation-of-the-pedunculopontine-nucleus-for-thetreatment-of-alzheimer-s-diseaseGamma oscillations (GO) are electrical signals detected in the brain that are essential for memory and cognition. Project Overview Gamma oscillations (GO) are electrical signals detected in the brain that are essential for memory and cognition. GO are a product of the activity of a subpopulation of...
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De grands esprits canadiens travaillent à percer les mystères du cerveau
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/de-grands-esprits-canadiens-travaillent-à-percer-les-mystères-du-cerveauPour publication immédiate Le 21 mars 2018 Montréal, QC Brain Canada élit à son Conseil d'administration des leaders canadiens issus du monde des affaires, de l'enseignement, des communautés autochtones et de la philanthropie Brain Canada est ravi d'annoncer l'élection de quatre nouveaux membres à...
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De la blessure à la défense des droits
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/du-préjudice-à-la-défense-des-intérêtsAprès avoir presque tout perdu à la suite d'une hémorragie cérébrale spontanée, Bob Murphy défend aujourd'hui les intérêts des personnes handicapées qui souffrent de pénurie alimentaire. Début 2011, un dimanche matin, Bob allait jouer au golf avec ses amis lorsqu'il a eu mal à la tête. Il a fait...
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De nouvelles collaborations pourraient permettre de traiter plus efficacement les patients atteints de SLA
https://braincanada.ca/fr/à-propos-de/nouvelles-mises-à-jour/de-nouvelles-collaborations-pourraient-permettre-de-traiter-plus-efficacement-les-patients-atteints-d-als"Il y a tout un écosystème dans le système nerveux central. Cette recherche fournit un lien direct avec ce qui pourrait réellement se passer lorsque les neurones sont suractivés. Si nous parvenons à comprendre la base de ce phénomène, nous pourrons alors cibler ce processus avec des produits...
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Deciphering eEF2K biological functions for therapeutic targeting of neural tumours
https://braincanada.ca/fr/subventions-financées/deciphering-eef2k-biological-functions-for-therapeutic-targeting-of-neural-tumoursIn childhood, medulloblastoma (a form of brain cancer) and neuroblastoma (a cancer that starts in the nerve cells) can be aggressive and hard to treat. Project Overview In childhood, medulloblastoma (a form of brain cancer) and neuroblastoma (a cancer that starts in the nerve cells) can be...
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Deciphering the link between gut bacteria and glymphatics in neurodegeneration
https://braincanada.ca/fr/subventions-financées/deciphering-the-link-between-gut-bacteria-and-glymphatics-in-neurodegenerationAmyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in humans. Project Overview Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in humans. The disease is caused by the degeneration of motor neurons that innervate the voluntary...
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Decoding motor cortex circuit abnormalities at ALS onset through combined two-photon imaging in vivo and pharmacogenetics
https://braincanada.ca/fr/subventions-financées/decoding-motor-cortex-circuit-abnormalities-at-als-onset-through-combined-two-photon-imaging-in-vivo-and-pharmacogeneticsALS is a disease that is characterized by degeneration of both upper and lower motor neurons, and while a significant proportion of work has focused on motor neurons in the spinal cord, the motor cortex in the brain, where electrical signals to your muscles originate have clear, but poorly Project...
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Decoding the RNA stability programs that determine cell identity and function in human brain and neurodegenerative disorders
https://braincanada.ca/fr/subventions-financées/decoding-the-rna-stability-programs-that-determine-cell-identity-and-function-in-human-brain-and-neurodegenerative-disordersThe brain cells in Alzheimer’s disease patients differ extensively from healthy brain cells at the molecular level: there are hundreds of genes that are normally active in the brain, but become inactive in Alzheimer’s. Project Overview The brain cells in Alzheimer’s disease patients differ...
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Decoding the Spatial Architecture of Newborn Brain Injury
https://braincanada.ca/fr/subventions-financées/decoding-the-spatial-architecture-of-newborn-brain-injuryInfants born early (preterm) are at risk for brain injury and long term neurodevelopmental challenges, including delays in walking, language development, and school-aged cognitive performance. Project Overview Infants born early (preterm) are at risk for brain injury and long term...
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Deep neural networks applied to interictal EEG to improve the diagnosis of epilepsy
https://braincanada.ca/fr/subventions-financées/deep-neural-networks-applied-to-interictal-eeg-to-improve-the-diagnosis-of-epilepsyEpilepsy is a debilitating disease affecting 1% of the world’s population. Project Overview Epilepsy is a debilitating disease affecting 1% of the world’s population. It is characterized by an enduring propensity to recurring seizures. One of the cornerstones of the diagnosis and management of...